Vichyanond Pakit, Pensrichon Rattana, Kurasirikul Suruthai
Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Asia Pac Allergy. 2012 Jan;2(1):15-25. doi: 10.5415/apallergy.2012.2.1.15. Epub 2012 Jan 31.
Asthma has become the most common chronic disease in childhood. Significant advances in epidemiological research as well as in therapy of pediatric asthma have been made over the past 2 decades. In this review, we look at certain aspects therapy of childhood asthma, both in the past and present. Literature review on allergen avoidance (including mites, cockroach and cat), intensive therapy with β(2)-agonists in acute asthma (administering via continuous nebulization and intravenous routes), a revisit of theophylline use and its action, the use of inhaled corticosteroids in various phases of childhood asthma and sublingual immunotherapy in asthma are examined. Recent facts and dilemmas of these treatments are identified along with expression of our opinions, particularly on points of childhood asthma in the Asia-Pacific, are made in this review.
哮喘已成为儿童期最常见的慢性疾病。在过去20年里,儿童哮喘的流行病学研究和治疗都取得了重大进展。在这篇综述中,我们探讨儿童哮喘治疗的某些方面,包括过去和现在的情况。我们研究了关于避免过敏原(包括螨虫、蟑螂和猫)、急性哮喘中β(2)受体激动剂的强化治疗(通过持续雾化和静脉途径给药)、茶碱使用及其作用的重新审视、吸入性糖皮质激素在儿童哮喘各阶段的应用以及哮喘的舌下免疫治疗等方面的文献。本文确定了这些治疗方法的最新情况和困境,并表达了我们的观点,特别是关于亚太地区儿童哮喘的问题。