Department of Dermatology, University of California-Irvine, Irvine, CA 92697, USA.
Int J Dermatol. 2012 Mar;51(3):250-62. doi: 10.1111/j.1365-4632.2011.05205.x.
Cigarette smoking has been associated with significant morbidity affecting all systems of the body, including the integumentary system. We review the many dermatologic hazards of tobacco use. It is important to distinguish between the effects of tobacco smoke from effects of pure nicotine on the skin. All skin cells express several subtypes of the nicotinic class of acetylcholine receptors, including the α7 receptor. Many chronic dermatoses are affected by smoking either negatively or positively. Elucidation of positive associations with a particular disease can lead to improvement from smoking cessation, whereas inverse correlation may lead to development of a disease-specific treatment with nicotinergic agonists.
吸烟与显著的发病率有关，影响身体的所有系统，包括皮肤系统。我们回顾了烟草使用的许多皮肤科危害。重要的是要区分烟草烟雾的影响和纯尼古丁对皮肤的影响。所有皮肤细胞都表达几种乙酰胆碱受体的烟碱类亚型，包括 α7 受体。许多慢性皮肤病受到吸烟的负面影响或正面影响。阐明与特定疾病的正相关关系可以导致戒烟的改善，而相反的相关性可能导致具有烟碱能激动剂的疾病特异性治疗的发展。
