Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.
Neuroradiology. 2012 Oct;54(10):1089-97. doi: 10.1007/s00234-012-1020-1. Epub 2012 Feb 21.
The purpose of this study was to propose new magnetic resonance (MR) criteria of diagnosing moyamoya disease (MMD) from cisternal moyamoya vessels (MMVs) on 3-T magnetic resonance imaging (MRI)/magnetic resonance angiography (MRA) and compare the diagnostic accuracy of the existing MR criteria and the proposed MR criteria.
Participants comprised 20 consecutive patients with MMD (4 males, 16 females) diagnosed clinically using conventional angiography and 20 controls (13 male and 7 female arteriosclerosis patients). In these participants, 3-T MRI/MRA was evaluated by the existing MR criteria, which use MMVs in the basal ganglia, and the proposed MR criteria, which use cisternal MMVs, and then these two criteria were statistically compared by McNemar's test.
Diagnostic accuracy was 62.5% with the existing MR criteria and 97.5% with the proposed MR criteria. The proposed MR criteria was more sensitive (1.00) than the existing MR criteria (0.45), but less specific (0.95) than the existing MR criteria (1.00).
The proposed MR criteria using cisternal MMVs showed significantly higher diagnostic accuracy than the existing MR criteria. We believe that our proposed MR criteria will be beneficial for diagnosing MMD.
本研究旨在提出一种新的磁共振（MR）标准，用于通过 3T 磁共振成像（MRI）/磁共振血管造影（MRA）从脑底异常血管网（MMV）中诊断烟雾病（MMD），并比较现有的 MR 标准和新提出的 MR 标准的诊断准确性。
本研究纳入了 20 例连续的 MMD 患者（4 名男性，16 名女性），这些患者均通过常规血管造影术进行临床诊断，以及 20 名对照组患者（13 名男性和 7 名女性动脉硬化患者）。在这些参与者中，使用现有的 MR 标准评估基底节 MMV，以及新提出的 MR 标准评估鞍上池 MMV，然后使用 McNemar 检验对这两种标准进行统计学比较。
现有的 MR 标准的诊断准确性为 62.5%，新提出的 MR 标准的诊断准确性为 97.5%。新提出的 MR 标准比现有的 MR 标准更敏感（1.00），但特异性较低（0.95）。
使用鞍上池 MMV 的新提出的 MR 标准比现有的 MR 标准具有更高的诊断准确性。我们相信，我们提出的 MR 标准将有助于诊断 MMD。
