International Centre for Life Course Studies in Society and Health, London, UK.
J Epidemiol Community Health. 2012 Oct;66(10):962-6. doi: 10.1136/jech-2011-200310. Epub 2012 Feb 21.
Whether the quality of life (QOL) impacts longevity is an interesting research question that has been investigated only in the context of disease and health-related QOL. This paper aims to examine prospectively whether Control, Autonomy, Self-realisation, and Pleasure (CASP) scores, a measure of generic QOL, can predict mortality in the British Household Panel Survey sample during 2001-2006.
The authors used data from the British Household Panel Survey wave 11 (2001-2002) when CASP was first presented to the participants in the survey. The authors selected all those who were interviewed directly and face to face and who were 40 years or older (N=10,291). The authors followed them for the next five waves (waves 12-16) and in this study primary outcome was all-cause mortality. Other covariates used were age, sex, socioeconomic position, household income, self-rated health, limiting long-standing illness and medical conditions.
Compared with a mortality of 12/1000 person-years in those having average QOL (CASP score 29.4-45.8), those with below-average QOL had more than twice (27/1000 person-years) and those above average had a third less (8/1000 person-years) mortality. This gradient was retained for the most part when age and sex strata were examined separately. Regression models adjusted for covariates confirmed the protective effect of QOL on mortality. Domain-specific analysis showed that only control and self-realisation had this effect.
CASP predicted 5-year all-cause mortality significantly. Improvement in the QOL reduced the probability of death.
生活质量(QOL)是否影响寿命是一个有趣的研究问题,仅在疾病和与健康相关的 QOL 背景下进行了研究。本文旨在前瞻性地研究控制、自主、自我实现和愉悦(CASP)评分(一种衡量通用 QOL 的指标)是否可以预测 2001-2006 年期间英国家庭面板调查样本中的死亡率。
作者使用了英国家庭面板调查第 11 波(2001-2002 年)的数据,当时 CASP 首次在调查中呈现给参与者。作者选择了所有直接和面对面接受访谈且年龄在 40 岁或以上的人(N=10,291)。作者对他们进行了接下来的五波(第 12-16 波)随访,本研究的主要结果是全因死亡率。其他使用的协变量包括年龄、性别、社会经济地位、家庭收入、自评健康、长期限制疾病和医疗状况。
与 QOL 平均值(CASP 评分 29.4-45.8)的人群相比,死亡率为 12/1000 人年,QOL 较低的人群死亡率高出两倍多(27/1000 人年),QOL 较高的人群死亡率低三分之一(8/1000 人年)。当按年龄和性别分层分别检查时,这种梯度在很大程度上得到保留。调整协变量的回归模型证实了 QOL 对死亡率的保护作用。特定领域的分析表明,只有控制和自我实现具有这种效果。
CASP 显著预测了 5 年全因死亡率。QOL 的改善降低了死亡的可能性。