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白斑病变可否有效治疗?

Can white spot lesions be treated effectively?

机构信息

Department of Orthodontics, Faculty of Dentistry, University of Selçuk, Konya, Turkey.

出版信息

Angle Orthod. 2012 Sep;82(5):770-5. doi: 10.2319/090711.578.1. Epub 2012 Feb 23.

Abstract

OBJECTIVE

To compare the effects of sodium fluoride mouth rinse, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and the microabrasion technique in treating white spot lesions.

MATERIALS AND METHODS

The study population consisted of 80 patients (46 females, 34 males; 966 affected teeth) who had developed multiple decalcified enamel lesions after fixed orthodontic therapy. The study population was divided into four groups of 20 patients each. The control group (group I) participants were to just brush their teeth, the fluoride group (group II) participants were instructed to use 20 ml of neutral 0.025% sodium fluoride rinse, the participants in the CPP-ACP group (group III) were instructed to use tooth mousse twice a day in addition to fluoride toothpaste for 6 months, and the participants in the microabrasion group (group IV) were to undergo treatment by the microabrasion technique, which is a commonly used mixture of 18% hydrochloric acid. Data were analyzed with the generalized linear mixed model and Tukey HSD at the P < .05 level.

RESULTS

The area of the white spot lesions decreased significantly in all groups. Inter group differences in the treatment success rates were significant. The highest success rate was observed for group IV (97%). The success rate of group III (58%) was significantly higher than that of groups II (48%) and I (45%).

CONCLUSIONS

The use of CPP-ACP can be more beneficial than fluoride rinse for postorthodontic remineralization. Microabrasion is an effective treatment for cosmetic improvement of long-standing white spot lesions.

摘要

目的

比较氟化钠漱口液、酪蛋白磷酸肽-无定形磷酸钙(CPP-ACP)和微研磨技术在治疗白斑病中的效果。

材料与方法

研究对象为 80 名患者(46 名女性,34 名男性;966 颗受累牙),他们在固定正畸治疗后出现了多个脱矿釉质病变。将研究人群分为四组,每组 20 名患者。对照组(I 组)患者只需刷牙,氟化物组(II 组)患者被指示使用 20ml 中性 0.025%的氟化钠漱口液,CPP-ACP 组(III 组)的患者被指示除了使用含氟牙膏外,每天使用两次牙慕斯,共 6 个月,微研磨组(IV 组)的患者接受微研磨技术治疗,该技术是一种常用的 18%盐酸混合物。使用广义线性混合模型和 Tukey HSD 在 P<0.05 水平进行数据分析。

结果

所有组的白斑病面积均显著减小。各组间治疗成功率的差异具有统计学意义。IV 组的成功率最高(97%)。III 组(58%)的成功率明显高于 II 组(48%)和 I 组(45%)。

结论

CPP-ACP 的使用对于正畸后再矿化可能比氟化物漱口液更有益。微研磨是改善长期存在的白斑病美观的有效治疗方法。

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