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古巴出现新型疑似传染性支气管炎病毒基因型的首例证据。

First evidence of the emergence of novel putative infectious bronchitis virus genotypes in Cuba.

机构信息

Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba.

出版信息

Res Vet Sci. 2012 Oct;93(2):1046-9. doi: 10.1016/j.rvsc.2012.01.012. Epub 2012 Feb 21.

Abstract

The emergence of new infectious bronchitis virus (IBV) genotypes or serotypes along with the poor cross-protection observed among IBV serotypes have complicated the avian infectious bronchitis (IB) control programs in different geographic regions. In Cuba, the lack of genetic information regarding IBV and the increasing epidemiological importance of this virus in Cuban chicken flocks demand further characterization of IBV isolates. In the present work, studies of genetic diversity and phylogenetic relationships among recent IBV isolates from Cuban chicken flocks showing respiratory disorders were performed. Two putative genotypes genetically different to the Massachusetts genotype H120 strain used in the Cuban vaccination program were found in the flocks assessed. In addition, a potential nephropathogenic IBV isolate was found by first time in Cuba.

摘要

新的传染性支气管炎病毒(IBV)基因型或血清型的出现,以及 IBV 血清型之间观察到的交叉保护效果不佳,使得不同地理区域的禽类传染性支气管炎(IB)控制计划变得复杂。在古巴,由于缺乏关于 IBV 的遗传信息,以及该病毒在古巴鸡群中的流行病学重要性不断增加,因此需要进一步对 IBV 分离株进行特征描述。在本工作中,对表现出呼吸障碍的古巴鸡群中的近期 IBV 分离株进行了遗传多样性和系统进化关系研究。在评估的鸡群中发现了两种与古巴免疫接种计划中使用的马萨诸塞型 H120 株在遗传上不同的假定基因型。此外,古巴首次发现了一种潜在的致肾病性 IBV 分离株。

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