[温州地区小学生热性惊厥的流行病学调查]

[An epidemiological survey of febrile convulsions among pupils in the Wenzhou region].

作者信息

Shi Xu-Lai, Lin Zhong-Dong, Ye Xiu-Yun, Hu Ying, Zheng Fei-Xia, Hu Hong-Wen

机构信息

Department of Neurology, Yuying Children's Hospital Affiliated to Wenzhou Medical College, Wenzhou, Zhejiang , China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2012 Feb;14(2):128-30.

PMID:22357472

Abstract

OBJECTIVE

To study the prevalence and clinical features of febrile convulsion (FC) among pupils in the Wenzhou region, Zhejiang Province, China.

METHODS

Using a random stratified cluster sampling method, 6406 children under 12 years from two primary schools of urban areas and two primary schools of rural areas were surveyed.

RESULTS

The prevalence of FC was 3.67% (235/6406). Most children (75.7%) experienced their first onset of FC at 6 months to 3 years of age (median: 16 months). The seizures were generalized (95.3%, 224/235), with a duration of less than 10 minutes (86.4%, 203/235). FC was developed into epilepsy in 13 children (5.5%) who all suffered from complex FC. Relapses were noted in 88 cases (37.4%), among whom 38 patients had only 1 recurrence and 50 patients had 2 or more relapses. EEG was performed in 200 cases, among whom 12(6.0%) showed abnormalities.

CONCLUSIONS

The prevalence of FC is 3.67% among pupils in the Wenzhou region. The seizures are generalized, with a short duration. A part of complex FC can be developed into subsequent epilepsy.

摘要

目的

研究中国浙江省温州市地区小学生热性惊厥（FC）的患病率及临床特征。

方法

采用随机分层整群抽样方法，对市区两所小学和农村两所小学的6406名12岁以下儿童进行调查。

结果

FC的患病率为3.67%（235/6406）。大多数儿童（75.7%）首次发生FC的年龄在6个月至3岁之间（中位数：16个月）。惊厥为全身性（95.3%，224/235），持续时间小于10分钟（86.4%，203/235）。13名儿童（5.5%）的FC发展为癫痫，这些儿童均患有复杂性FC。88例（37.4%）出现复发，其中38例仅复发1次，50例复发2次或更多次。对200例进行了脑电图检查，其中12例（6.0%）显示异常。