Klimiuk P S, Davies M, Adams P H
Postgrad Med J. 1981 Feb;57(664):80-3. doi: 10.1136/pgmj.57.664.80.
Six patients receiving thiazide diuretics were referred for evaluation of mild to moderate hypercalcaemia (serum calcium 2.65-2.98 mmol/l). All patients were considered to be suffering from primary hyperparathyroidism. Withdrawal of the diuretic was followed by a reduction in the serum calcium, one patient becoming normocalcaemia. The mechanisms responsible for these changes are discussed. In hypercalcaemic patients taking thiazides, it is recommended that the effects of withholding the diuretic should be observed before more radical measures are considered.
6名正在接受噻嗪类利尿剂治疗的患者因轻度至中度高钙血症（血清钙2.65 - 2.98 mmol/L）前来接受评估。所有患者均被认为患有原发性甲状旁腺功能亢进症。停用利尿剂后血清钙水平下降，1例患者血钙恢复正常。文中讨论了导致这些变化的机制。对于服用噻嗪类药物的高钙血症患者，建议在考虑采取更激进的措施之前，先观察停用利尿剂的效果。
