Hong Soyoung, Son Dong Koog, Lim Wan Ryung, Kim Sun Hang, Kim Hyunjung, Yum Hye Yung, Kwon Hojang
Atopy Research Institute, Seoul Medical Center, Seoul, Korea.
Environ Health Toxicol. 2012;27:e2012006. doi: 10.5620/eht.2012.27.e2012006. Epub 2012 Feb 13.
Childhood allergic diseases are a major concern because they lead to a heavy economic burden and poor quality of life. The purpose of this study was to investigate the prevalence of childhood atopic dermatitis, asthma, allergic rhinitis, and the comorbidity of allergic diseases in Seoul, Korea.
We conducted a cross-sectional survey between May and October 2010 to evaluate the prevalence of childhood allergic diseases, including atopic dermatitis, asthma, and allergic rhinitis, using a questionnaire from the International Study of Asthma and Allergies in Childhood group. Each questionnaire was completed by the parent or guardian of a child.
In the 31,201 children studied, the prevalence of atopic dermatitis symptoms in the past 12 months was 19.3% in children 0 to 3 years of age, 19.7% in children 4 to 6 years of age, 16.7% in children 7 to 9 years of age, and 14.5% in children 10 to 13 years of age (p for trend < 0.001). The prevalence of asthma in these age groups was 16.5%, 9.8%, 6.5%, and 5.4%, respectively (p for trend < 0.001). The prevalence of allergic rhinitis in these age groups was 28.5%, 38.0%, 38.5%, and 35.9%, respectively (p for trend = 0.043). The percentage of subjects with both atopic dermatitis and asthma, both asthma and allergic rhinitis, or both atopic dermatitis and allergic rhinitis was 2.5%, 4.7%, and 8.7%, respectively. The prevalence of comorbid allergic diseases decreased with age (p for trend < 0.001).
Our study revealed that the prevalence of some allergic diseases, such as atopic dermatitis and asthma, was relatively high in very young children and that all of the principal allergic diseases in children often co-exist.
儿童过敏性疾病是一个主要问题，因为它们会导致沉重的经济负担和生活质量下降。本研究的目的是调查韩国首尔儿童特应性皮炎、哮喘、过敏性鼻炎的患病率以及过敏性疾病的合并症情况。
我们在2010年5月至10月期间进行了一项横断面调查，使用儿童哮喘和过敏国际研究组的问卷来评估儿童过敏性疾病（包括特应性皮炎、哮喘和过敏性鼻炎）的患病率。每份问卷由儿童的父母或监护人填写。
在研究的31201名儿童中，过去12个月内特应性皮炎症状的患病率在0至3岁儿童中为19.3%，4至6岁儿童中为19.7%，7至9岁儿童中为16.7%，10至13岁儿童中为14.5%（趋势p<0.001）。这些年龄组中哮喘的患病率分别为16.5%、9.8%、6.5%和5.4%（趋势p<0.001）。这些年龄组中过敏性鼻炎的患病率分别为28.5%、38.0%、38.5%和35.9%（趋势p = 0.043）。同时患有特应性皮炎和哮喘、哮喘和过敏性鼻炎或特应性皮炎和过敏性鼻炎的受试者百分比分别为2.5%、4.7%和8.7%。合并过敏性疾病的患病率随年龄下降（趋势p<0.001）。
我们的研究表明，一些过敏性疾病，如特应性皮炎和哮喘，在幼儿中的患病率相对较高，并且儿童所有主要的过敏性疾病往往同时存在。
