Jang Woo Sun, Lee Jin Woong, Yoo Kwang Ho, Park Kui Young, Han Tae Young, Li Kapsok, Seo Seong Jun, Hong Chang Kwun
Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea.
Ann Dermatol. 2012 Feb;24(1):81-3. doi: 10.5021/ad.2012.24.1.81. Epub 2012 Feb 2.
Linear focal elastosis (LFE) is characterized by several asymptomatic, yellow, palpable, irregularly indurated, striae-like lines extending horizontally across the middle and lower back. A focal increase in elastic fibers is a hallmark of the disease as seen from biopsy specimens. The pathogenesis of LFE is unclear, as is the association between LFE and striae distensae (SD). However, the prevailing opinion is that LFE represents an excessive regenerative process of elastic fibers and is analogous to keloidal repair of SD. Although the timing of onset of LFE and SD was not synchronous in our patient, the triggering factor was the same, which was the growth spurt. This case is supporting the putative association between LFE and SD.
线性局灶性弹性组织变性(LFE)的特征为多条无症状的黄色、可触及的、不规则硬结的、条纹状的线,水平延伸穿过中下背部。从活检标本可见弹性纤维局灶性增加是该病的一个标志。LFE的发病机制尚不清楚,LFE与膨胀纹(SD)之间的关联也不明确。然而,普遍观点认为LFE代表弹性纤维的过度再生过程,类似于SD的瘢痕疙瘩样修复。虽然我们的患者中LFE和SD的发病时间不同步,但触发因素相同,即生长突增。该病例支持了LFE与SD之间的假定关联。