Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
Clin Exp Dermatol. 2023 Mar 1;48(3):175-180. doi: 10.1093/ced/llac071.
Linear focal elastosis (LFE) is an uncommon, benign, acquired elastotic condition with uncertain pathogenesis. It is characterized clinically by asymptomatic, multiple, yellowish, elevated, irregularly indurated, striae-like lines or bands distributed horizontally across the lower and middle part of the posterior trunk. The histopathological hallmark of LFE is a focal increase of elastic fibres in the dermis. The differential diagnosis is varied, and striae distensae is the closest mimic of LFE. Response of LFE to treatment is often poor. The focus of this article is to provide insights into this condition for dermatologists.
线性局灶性弹力纤维病(LFE)是一种罕见的良性获得性弹力纤维病,其发病机制尚不清楚。其临床特征为无症状、多发性、黄色、隆起、不规则硬化、条纹状线或带,水平分布于后躯干中下部分。LFE 的组织病理学特征是真皮中弹力纤维的局灶性增加。鉴别诊断多种多样,而膨胀纹是 LFE 最接近的模拟物。LFE 对治疗的反应往往不佳。本文的重点是为皮肤科医生提供对此种疾病的深入了解。