Virology Department, Faculty of Veterinary Medicine, Ankara University, Diskapi, Turkey.
Arch Virol. 2012 Jun;157(6):1183-7. doi: 10.1007/s00705-012-1263-5. Epub 2012 Feb 26.
Group A rotaviruses are regarded as major enteric pathogens of large ruminants, while their impact on the health of small ruminants is not well documented. We report the detection of group A rotavirus from a large outbreak of enteritis that occurred in two goat flocks in the town of Kırklareli, Marmara Region, Turkey, in 2007. The disease was observed in young kids, with high morbidity and mortality rates, but not in adult animals. Rotavirus antigen was detected in the stools of the examined animals, and rotaviruses were isolated in MA104 cells. Upon sequencing of the VP4, VP6, VP7 and NSP4 genes, the strain (RVA/goat-tc/TUR/Kirklareli/2007/G8P[1]) was characterized as G8P[1], with E2 NSP4 and VP6 I2 genotype. These findings indicate that group A rotavirus should be included in the diagnostic algorithms for enteric disease in small ruminants.
A 组轮状病毒被认为是大型反刍动物的主要肠道病原体,但其对小型反刍动物健康的影响尚未得到充分记录。我们报告了在 2007 年土耳其马尔马拉地区基尔克拉雷利镇的两个山羊群中发生的大规模肠炎大爆发中检测到 A 组轮状病毒。该疾病发生在幼崽中,发病率和死亡率很高,但在成年动物中没有发现。在检查动物的粪便中检测到轮状病毒抗原,并在 MA104 细胞中分离出轮状病毒。对 VP4、VP6、VP7 和 NSP4 基因进行测序后,该菌株(RVA/goat-tc/TUR/Kirklareli/2007/G8P[1])被鉴定为 G8P[1],具有 E2 NSP4 和 VP6 I2 基因型。这些发现表明,A 组轮状病毒应被纳入小型反刍动物肠道疾病的诊断算法中。