Feng Jing, Feng Zhi-Yi, Wang Jun-Ming, Cui Ying
Henan College of Traditional Chinese Medicine, Zhengzhou 450003, China.
Zhong Yao Cai. 2011 Oct;34(10):1540-4.
To study the triterpenoids from the fruits of Ligustrum lucidum.
The constituents were extracted with 95% EtOH, partitioned with different solvents, isolated and purified by silica gel, Sephadex LH-20 and PHPLC column chromatography. The structures were elucidated by physicochemical properties and spectroscopic data.
Thirteen compounds were isolated and identified as methyl oleanolate (1), 3-O-acetylursolic acid (2), 3-ketooleanolic acid (3), 19alpha-hydroxyl ursolic acid (4), lupeol (5), 3-O-acetyl oleanolic acid (6), oleanolic acid (7), betulin (8), ursolic acid (9), fouquierol (10), 19alpha-hydroxyl acetylursolic acid (11), 3-O-cis-P-coumaroyl maslinic acid (12) and 3-O-trans-P-coumaroyl maslinic acid (13).
Compounds 1 - 4 are obtained from this plant for the first time.
研究女贞果实中的三萜类化合物。
用95%乙醇提取其成分，经不同溶剂萃取后，通过硅胶柱色谱、葡聚糖凝胶LH - 20柱色谱和制备型高效液相色谱柱色谱进行分离纯化。利用理化性质和光谱数据对其结构进行鉴定。
分离得到13个化合物，分别鉴定为齐墩果酸甲酯（1）、3 - O - 乙酰乌索酸（2）、3 - 酮基齐墩果酸（3）、19α - 羟基乌索酸（4）、羽扇豆醇（5）、3 - O - 乙酰齐墩果酸（6）、齐墩果酸（7）、桦木醇（8）、乌索酸（9）、福桂醇（10）、19α - 羟基乙酰乌索酸（11）、3 - O - 顺式 - 对香豆酰山楂酸（12）和3 - O - 反式 - 对香豆酰山楂酸（13）。
化合物1 - 4首次从该植物中获得。
