Lynge E, Thygesen L
Danish Cancer Society, Danish Cancer Registry, Copenhagen, Denmark.
Scand J Work Environ Health. 1990;16 Suppl 2:3-35.
Data sources and creation of data files. The cohort of persons who were 20-64 years of age at the time of the 1970 census has been followed for cancer incidence for a ten-year period. The study was made by linkage of individual records from the 1970 census, the Central Population Register, death certificates, and cancer registrations. Data were included on individual characteristics recorded in the census on prevalent cancer cases at the time of the census and on deaths, emigrations, and incident cancer cases during the ten-year follow-up period. The study includes a total of 2.8 million persons, of whom 2.0 million were economically active at the time of the 1970 census. A total of 115,000 incident cancer cases were registered during the follow-up period, and 77,000 of these occurred in persons who were economically active in 1970. The classifications used in the census included 218 codes for occupation and 245 codes for industry. The Cancer Registry data included 639 codes for diagnosis. Cancer incidence by social groups in Denmark. The cancer incidence was tabulated across 32 socioeconomic groups for 43 cancer sites among the men and 45 cancer sites among the women. The study showed an almost twofold difference in the overall cancer incidence between the socioeconomic groups of the men. Self-employed farmers were at low risk (RR 0.68), and unskilled workers in shipping/fishing were at high risk (RR 1.28) when the cancer incidence among all economically active men was used for the comparison. The social pattern in cancer incidence correlated well with the pattern for cancer mortality among men. As a rough estimate, the cumulative incidence for all cancer among persons under 75 years of age could be reduced by 32% if all Danish men had the cancer incidence of farmers. There was a fivefold or larger difference between the socioeconomic groups in the incidence for nine cancer sites. These nine cancer sites together represented 7% of the cumulative incidence for all cancer. Estimated in a similar way, the cumulative incidence could be reduced by 44% if all Danish men had the site-specific cancer incidence of the respective low-risk groups. The overall cancer incidence among the women varied from a relative risk of 0.71 for unskilled workers in agriculture to a relative risk of 1.18 for self-employed women in other industries I (dentists, lawyers, etc) when the cancer incidence among all economically active women was used for the comparison.(ABSTRACT TRUNCATED AT 400 WORDS)
数据来源与数据文件的创建。对在1970年人口普查时年龄为20 - 64岁的人群队列进行了为期十年的癌症发病率跟踪研究。该研究通过将1970年人口普查、中央人口登记册、死亡证明和癌症登记的个人记录相链接来开展。数据包括人口普查时记录的个人特征、普查时的现患癌症病例以及十年随访期内的死亡、移民和新发癌症病例。该研究共纳入280万人，其中200万人在1970年人口普查时处于经济活跃状态。随访期内共登记了11.5万例新发癌症病例，其中7.7万例发生在1970年经济活跃的人群中。人口普查中使用的分类包括218个职业代码和245个行业代码。癌症登记数据包括639个诊断代码。丹麦不同社会群体的癌症发病率。按32个社会经济群体列出了男性43个癌症部位和女性45个癌症部位的癌症发病率。研究表明，男性社会经济群体之间的总体癌症发病率几乎相差两倍。以所有经济活跃男性的癌症发病率作为比较基准时，个体经营的农民风险较低（相对风险RR为0.68），而航运/渔业领域的非技术工人风险较高（RR为1.28）。癌症发病率的社会模式与男性癌症死亡率模式密切相关。粗略估计，如果所有丹麦男性的癌症发病率都与农民相同，75岁以下人群所有癌症的累积发病率可降低32%。九个癌症部位的发病率在社会经济群体之间相差五倍或更大。这九个癌症部位合计占所有癌症累积发病率的7%。以类似方式估计，如果所有丹麦男性的特定部位癌症发病率都与各自低风险群体相同，累积发病率可降低44%。以所有经济活跃女性的癌症发病率作为比较基准时，女性的总体癌症发病率从农业领域非技术工人的相对风险0.71到其他行业I（牙医、律师等）个体经营女性的相对风险1.18不等。（摘要截选至400字）
