Zuo Wen-Jian, Dai Hao-Fu, Zeng Yan-Bo, Wang Hui, Chen Hui-Qin, Wang Jin-Hui
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
J Asian Nat Prod Res. 2012;14(4):308-13. doi: 10.1080/10286020.2011.653347.
Two new triterpene saponins, ilekudinchosides F (1) and G (2), along with three known saponins were isolated from the leaves of Ilex kudingcha C. J. Tseng. The new compounds were characterized as 3β,19α-dihydroxy-12α-ethoxy-urs-13(18)-ene-28,20β-lactone-3-O-[β-D-glucopyranosyl(1 → 3)]-[α-L-rhamnopyranosyl(1 → 2)]-α-L-arabinopyranoside (1) and 3β,19α-dihydroxy-12α-methoxy-urs-13(18)-ene-28,20β-lactone-3-O-[α-L-rhamnopyranosyl(1 → 2)]-α-L-arabinopyranoside (2). The new structures were elucidated by spectroscopic methods including 1D and 2D NMR, HR-TOF-MS, and CD spectrometry, and the known compounds were identified by the comparison of their NMR and HR-TOF-MS data with those reported in the literature.
从苦丁茶冬青（Ilex kudingcha C. J. Tseng）的叶子中分离出两种新的三萜皂苷，即苦丁茶皂苷F（1）和G（2），以及三种已知的皂苷。新化合物被鉴定为3β,19α-二羟基-12α-乙氧基-乌苏-13(18)-烯-28,20β-内酯-3-O-[β-D-吡喃葡萄糖基(1→3)]-[α-L-鼠李吡喃糖基(1→2)]-α-L-阿拉伯吡喃糖苷（1）和3β,19α-二羟基-12α-甲氧基-乌苏-13(18)-烯-28,20β-内酯-3-O-[α-L-鼠李吡喃糖基(1→2)]-α-L-阿拉伯吡喃糖苷（2）。通过包括一维和二维核磁共振、高分辨飞行时间质谱和圆二色光谱法在内的光谱方法阐明了新结构，并通过将其核磁共振和高分辨飞行时间质谱数据与文献报道的数据进行比较鉴定了已知化合物。
