Department of Specific Formation, School of Dentistry, Fluminense Federal University, Nova Friburgo, Brazil.
Acta Odontol Scand. 2013 Jan;71(1):157-67. doi: 10.3109/00016357.2011.654255. Epub 2012 Mar 1.
To present a mucopolysaccharidosis (MPS) case series evaluating oral manifestations (clinical and radiographic), oral health status and discussing its implications.
All patients with MPS attending the Genetics clinic/Brazil were evaluated by means of anamnesis, clinical and radiographic examinations.
The final sample consisted of 12 subjects (nine males and three females), with ages ranging from 3-31 years old. Concerning oral health, it was observed high levels of caries and periodontal problems. About oral manifestations, this study clinically observed more cases of delayed tooth eruption, thickness of alveolar process and thick lips. Radiographically, it was observed alterations on condyle, mandibular ramus and joint fossa.
The dental changes in MPS population are high and consequently it is important to know them for differential diagnoses, early treatment intervention, prevention and education of both patients and parents/caregivers about oral health.
介绍一组黏多糖贮积症（MPS）病例，评估口腔表现（临床和影像学）、口腔健康状况，并讨论其影响。
对在遗传诊所/巴西就诊的所有 MPS 患者进行病史、临床和影像学检查。
最终样本包括 12 名患者（9 名男性和 3 名女性），年龄 3-31 岁。关于口腔健康，观察到龋齿和牙周问题的发生率较高。关于口腔表现，本研究临床观察到更多的牙齿萌出延迟、牙槽突增厚和嘴唇增厚的情况。影像学上，观察到髁突、下颌支和关节凹的改变。
MPS 人群的牙齿变化较多，因此了解这些变化对于鉴别诊断、早期治疗干预、预防以及对患者及其父母/照顾者进行口腔健康教育非常重要。
