肠出血性大肠杆菌 O104:H4 感染与国际旅行。
Escherichia coli O104:H4 infections and international travel.
机构信息
Public Health Ontario, Toronto, Ontario, Canada
出版信息
Emerg Infect Dis. 2012 Mar;18(3):473-6. doi: 10.3201/eid1803.111281.
Abstract
We analyzed travel-associated clinical isolates of Escherichia coli O104:H4, including 1 from the 2011 German outbreak and 1 from a patient who returned from the Philippines in 2010, by genome sequencing and optical mapping. Despite extensive genomic similarity between these strains, key differences included the distribution of toxin and antimicrobial drug-resistance determinants.
摘要
我们通过基因组测序和光学图谱分析了与旅行相关的大肠杆菌 O104:H4 临床分离株，包括 2011 年德国暴发疫情中的 1 株分离株和 2010 年从菲律宾返回的 1 例患者分离的 1 株。尽管这些菌株的基因组具有广泛的相似性，但关键差异包括毒素和抗菌药物耐药决定因素的分布。
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