RTI International, Research Triangle Park, NC, USA.
J Expo Sci Environ Epidemiol. 2012 May-Jun;22(3):274-80. doi: 10.1038/jes.2012.8. Epub 2012 Feb 29.
Personal exposure sampling provides the most accurate and representative assessment of exposure to a pollutant, but only if measures are implemented to minimize exposure misclassification and reduce confounders that may cause misinterpretation of the collected data. Poor compliance with personal sampler wearing protocols can create positive or negative biases in the reported exposure concentrations, depending on proximity of the participant or the personal sampler to the pollutant source when the monitor was not worn as instructed. This paper presents an initial quantitative examination of personal exposure monitor wearing protocol compliance during a longitudinal particulate matter personal exposure monitoring study of senior citizens of compromise health in North Carolina. Wearing compliance varied between participants because of gender or employment status, but not longitudinally or between cohorts. A minimum waking wearing compliance threshold, 0.4 for this study of senior citizens, is suggested to define when personal exposure measurements are representative of a participant's exposure. The ability to define a minimum threshold indicates data weighting techniques may be used to estimate a participant's exposure assuming perfect protocol compliance.
个人暴露采样提供了对污染物暴露最准确和最具代表性的评估，但只有在采取措施尽量减少暴露分类错误和减少可能导致对收集数据产生误解的混杂因素的情况下才如此。如果个人采样器佩戴协议的遵守情况不佳，根据监测器未按指示佩戴时参与者或个人采样器与污染物源的接近程度，报告的暴露浓度可能会产生正或负偏差。本文初步定量检查了北卡罗来纳州健康状况不佳的老年人进行的纵向颗粒物个人暴露监测研究期间个人暴露监测器佩戴协议的遵守情况。由于性别或就业状况的不同，参与者之间的佩戴合规性有所不同，但在纵向或队列之间没有差异。建议本项针对老年人的研究设定最小清醒佩戴合规性阈值为 0.4，以定义何时个人暴露测量能够代表参与者的暴露情况。定义最小阈值的能力表明，可以使用数据加权技术来估计参与者的暴露情况，前提是假设完全遵守协议。
