Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore, Singapore.
ChemSusChem. 2012 Apr;5(4):625-8. doi: 10.1002/cssc.201100649. Epub 2012 Feb 29.
AHA Erlebnis: CaC(2), used to produce acetylene until several decades ago, is re-emerging as a cheap, sustainable resource synthesized from coal and lignocellulosic biomass. We report efficient catalytic protocols for the synthesis of functional acetylene derivatives from CaC(2) through aldehyde, alkyne, and amine (AAA) as well as alkyne, haloalkane, and amine (AHA) couplings, and in addition demonstrate its use in click and Sonogashira chemistry, showing that calcium carbide is a sustainable and cost-efficient carbon source.
AHA 体验：碳化钙（CaC(2)）曾被用于生产乙炔，直到几十年前，它又重新成为一种从煤和木质纤维素生物质合成的廉价、可持续的资源。我们报告了通过醛、炔和胺（AAA）以及炔、卤代烷和胺（AHA）偶联从 CaC(2)合成功能乙炔衍生物的高效催化方案，此外还展示了其在点击和 Sonogashira 化学中的应用，表明碳化钙是一种可持续且具有成本效益的碳源。
