自我剪接的II类内含子和细胞核前体mRNA内含子：它们有多相似？
Self-splicing group II and nuclear pre-mRNA introns: how similar are they?
作者信息
Jacquier A
机构信息
Département de Biologie, Moléculaire, Institut Pasteur, Paris, France.
出版信息
Trends Biochem Sci. 1990 Sep;15(9):351-4. doi: 10.1016/0968-0004(90)90075-m.
PMID:2238045
Abstract
The splicing pathway of pre-mRNA introns bears similarities to that of the group II introns, some members of which undergo self-splicing. The snRNAs may provide the pre-mRNA introns with RNA structures in trans comparable to those available in cis in group II introns. This article examines the available evidence for the hypothesis that the catalysis of these two splicing pathways is fundamentally equivalent.
摘要
前体信使核糖核酸（pre-mRNA）内含子的剪接途径与II类内含子的剪接途径有相似之处，其中一些成员可进行自我剪接。小核核糖核酸（snRNAs）可能为前体信使核糖核酸内含子提供反式RNA结构，这些结构与II类内含子顺式存在的结构相当。本文研究了关于这两种剪接途径的催化作用在根本上是等效的这一假说的现有证据。
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