[低氧性缺氧对大鼠红细胞糖酵解酶活性的影响]
[The effect of hypoxic hypoxia on the activity of glycolysis enzymes in rat erythrocytes].
作者信息
Sukhomlinov B F, Antoniak G L, Ikpu B O
出版信息
Ukr Biokhim Zh (1978). 1990 Jul-Aug;62(4):90-3.
The oxygen-binding properties of hemoglobin, concentration of 2,3-diphosphoglycerate, activity of carbohydrate metabolism enzymes and kinetics of rat erythrocyte hemolysis have been studied at high altitudes. The hemoglobin affinity to oxygen, glycolysis enzyme activity and erythrocyte membrane resistance are established to increase at the initial period of adaptation. The activation of the pentose-phosphate pathway of the glucose, transformation and inhibition of the glycolytic process in these cells are observed on the 10th day.
在高海拔地区研究了血红蛋白的氧结合特性、2,3-二磷酸甘油酸的浓度、碳水化合物代谢酶的活性以及大鼠红细胞溶血的动力学。发现血红蛋白对氧的亲和力、糖酵解酶活性和红细胞膜抗性在适应初期会增加。在第10天观察到葡萄糖戊糖磷酸途径的激活、这些细胞中糖酵解过程的转变和抑制。
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