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JAK-STAT signaling: from interferons to cytokines.JAK-STAT信号传导:从干扰素到细胞因子
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本文引用的文献

1
Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies.细胞因子信号传导和骨髓增殖性疾病中的Jak/STAT信号通路:靶向治疗方法
Genes Cancer. 2010 Oct;1(10):979-93. doi: 10.1177/1947601910397187.
2
Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases.利用结构信息和化学遗传学开发 Janus 激酶抑制剂的前景。
J Cell Mol Med. 2010 Mar;14(3):504-27. doi: 10.1111/j.1582-4934.2010.01018.x. Epub 2010 Jan 28.
3
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.JAK2使组蛋白H3Y41磷酸化,并将HP1α排除在染色质之外。
Nature. 2009 Oct 8;461(7265):819-22. doi: 10.1038/nature08448. Epub 2009 Sep 27.
4
Janus kinases in immune cell signaling.免疫细胞信号传导中的 Janus 激酶
Immunol Rev. 2009 Mar;228(1):273-87. doi: 10.1111/j.1600-065X.2008.00754.x.
5
Canonical and non-canonical JAK-STAT signaling.经典和非经典JAK-STAT信号传导。
Trends Cell Biol. 2008 Nov;18(11):545-51. doi: 10.1016/j.tcb.2008.08.008. Epub 2008 Oct 9.
6
Inteferons pen the JAK-STAT pathway.干扰素开启JAK-STAT信号通路。 (注:原文中“ Inteferons ”应改为“ Interferons” )
Semin Cell Dev Biol. 2008 Aug;19(4):311-8. doi: 10.1016/j.semcdb.2008.08.010. Epub 2008 Aug 26.
7
Therapeutic targeting of Janus kinases.Janus激酶的治疗靶点
Immunol Rev. 2008 Jun;223:132-42. doi: 10.1111/j.1600-065X.2008.00644.x.
8
JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions.果蝇中的JAK/STAT信号传导:对保守调控和细胞功能的见解
Development. 2006 Jul;133(14):2605-16. doi: 10.1242/dev.02411.
9
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins.Jak-STAT信号通路以及对干扰素和其他细胞外信号蛋白的转录激活。
Science. 1994 Jun 3;264(5164):1415-21. doi: 10.1126/science.8197455.

Jak/STAT 通路。

The Jak/STAT pathway.

机构信息

Department of Biology, University of Kentucky, Lexington, Kentucky 40506, USA.

出版信息

Cold Spring Harb Perspect Biol. 2012 Mar 1;4(3):a011205. doi: 10.1101/cshperspect.a011205.

DOI:10.1101/cshperspect.a011205
PMID:22383755
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3282412/
Abstract

The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway mediates cellular responses to cytokines (e.g., IL-6) and growth factors (e.g., EGF).

摘要

Janus 激酶/信号转导子和转录激活子(JAK/STAT)信号通路介导细胞对细胞因子(如白细胞介素 6 [IL-6])和生长因子(如表皮生长因子 [EGF])的反应。