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[辅助生殖技术中的细菌性精液症:细菌对精子和精浆的影响、诊断与治疗]

[Bacteriospermia in Assisted Reproductive Techniques: effects of bacteria on spermatozoa and seminal plasma, diagnosis and treatment].

作者信息

Boitrelle F, Robin G, Lefebvre C, Bailly M, Selva J, Courcol R, Lornage J, Albert M

机构信息

Laboratoire de spermiologie, biologie de la reproduction, cytogénétique, CHI de Poissy-Saint-Germain-en-Laye, rue du Champ-Gaillard, 78303 Poissy, France.

出版信息

Gynecol Obstet Fertil. 2012 Apr;40(4):226-34. doi: 10.1016/j.gyobfe.2012.01.003. Epub 2012 Mar 3.

Abstract

The presence of bacteria in semen could induce impairment of sperm morphology, alteration of sperm function and mechanical or functional obstruction of the seminal tract. The term of bacteriospermia does not signify infection. Bacteriospermia and male accessory gland infection (MAGI) have indeed to be distinguished. They may lead both to male infertility but their diagnosis and treatment options differ. This review summarizes effects of bacteria and leucocytospermia on sperm parameters and functions. Then, indications, benefits and risks of treatment of bacteriospermia and MAGI, in assisted reproductive techniques (ART) will be discussed. For bacteria commonly observed in semen, this review aims at defining some thresholds above which a treatment is required. These thresholds were established according to literature, according to French microbiology society and in function of our usual practice. This review should help practitioners of reproductive medicine to take care of bacteriospermia in semen.

摘要

精液中细菌的存在可导致精子形态受损、精子功能改变以及生殖道的机械性或功能性梗阻。菌精症一词并不意味着感染。菌精症和男性附属腺感染(MAGI)确实需要加以区分。它们都可能导致男性不育,但它们的诊断和治疗方案有所不同。本综述总结了细菌和白细胞精子症对精子参数和功能的影响。然后,将讨论辅助生殖技术(ART)中菌精症和MAGI治疗的适应症、益处和风险。对于精液中常见的细菌,本综述旨在确定一些需要治疗的阈值。这些阈值是根据文献、法国微生物学会以及我们的常规做法确定的。本综述应有助于生殖医学从业者关注精液中的菌精症。

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