Section of Endocrinology, Andrology and Internal Medicine, Department of Medical and Pediatric Sciences, University of Catania, Catania, Italy.
J Endocrinol Invest. 2013 Oct;36(9):770-4. doi: 10.3275/8950. Epub 2013 Apr 30.
MAGI is an acronym that identifies the "male accessory gland inflammations/infections", a potential cause of male infertility. Type 2 diabetes mellitus (DM2) prevalence is going to increase among men of reproductive age. Due to the high prevalence of these two conditions, we could suppose that they might appear together in the same patient.
To evaluate MAGI prevalence in patients with DM2 in fertile age.
A cross-sectional study carried out on patients with DM2 of fertile age. All patients underwent andrological evaluation for the identification of conventional MAGI diagnostic criteria.
DM2 patients showed a frequency of MAGI about 43%, significantly lower (p<0.05) than in infertile patients of the same age without diabetes, which showed a MAGI overall frequency of 61%. Among examined diabetic patients the prevalence of MAGI did not significantly differ between patients attending for diabetes care problems (glycemic control) and patients with andrological disorders. Finally, no significant difference in seminal inflammatory signs frequency was detected between patients with DM2 and infertile patients without diabetes. Finally, the correlation analysis showed a significant direct correlation between duration of diabetes and glycemic control with the prevalence of MAGI.
MAGI prevalence in DM2 is lower than the one detected in age-matched infertile non-diabetic patients, however, as in infertile patients, there is a high frequency of seminal inflammatory signs. Moreover, the observed prevalence among diabetic patients with diabetes care problems and diabetic patients with andrological problems is not statistically different.
MAGI 是一个缩写，代表“男性附属腺体炎症/感染”，这是男性不育的潜在原因。2 型糖尿病（DM2）在育龄男性中的发病率将会增加。由于这两种情况的高发病率，我们可以假设它们可能同时出现在同一患者身上。
评估生育年龄 2 型糖尿病患者中 MAGI 的患病率。
这是一项在生育年龄的 2 型糖尿病患者中进行的横断面研究。所有患者均接受了男科评估，以确定常规 MAGI 诊断标准。
DM2 患者的 MAGI 频率约为 43%，明显低于（p<0.05）同年龄无糖尿病的不育患者，后者的 MAGI 总频率为 61%。在检查的糖尿病患者中，因糖尿病问题（血糖控制）就诊的患者和男科疾病患者之间的 MAGI 患病率没有显著差异。最后，在 DM2 患者和无糖尿病不育患者之间，未检测到精液炎症体征频率有显著差异。最后，相关性分析显示，糖尿病的持续时间和血糖控制与 MAGI 的患病率之间存在显著的直接相关性。
MAGI 在 DM2 中的患病率低于年龄匹配的不育非糖尿病患者，但与不育患者一样，精液炎症体征的发生率很高。此外，在有糖尿病问题和男科问题的糖尿病患者中，观察到的患病率在统计学上没有差异。
