Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
Eye (Lond). 2012 Jun;26(6):796-802. doi: 10.1038/eye.2012.23. Epub 2012 Mar 2.
To compare the intraocular pressure (IOP) after 23-gauge transconjunctival sutureless vitrectomy (TSV) and conventional 20-gauge vitrectomy for various vitreoretinal diseases.
This was a retrospective interventional case series including 338 cases of 23-gauge TSV and 476 cases of 20-gauge vitrectomy with minimum follow-up period of 1 month. Postoperative 1 day, 1 week and 1 month IOPs were compared. Multiple regression analysis to assess the actual effect of gauge of vitrectomy on postoperative IOP was performed including intraoperative and postoperative factors influencing postoperative IOP as covariates.
The mean IOP of 20-gauge vitrectomy was significantly higher than that of 23-gauge TSV (20.6 ± 8.02 mm Hg vs 12.8 ± 4.48 mm Hg, P<0.001) at postoperative day 1, but the differences were not significant at postoperative 1 week and 1 month. The IOP pattern of 23-gauge TSV demonstrated more stable course than that of 20-gauge vitrectomy. At 1 day post vitrectomy, the incidence of hypertony was higher in 20-gauge, whereas that of hypotony was higher in 23-gauge. Among risk factors, the 20-gauge vitrectomy showed the strongest association with postoperative 1 day IOP rise.
Twenty-three-gauge TSV has stable and lower IOP in the early postoperative period than the 20-gauge vitrectomy. In patients whose retina and optic nerves are vulnerable to higher or fluctuating IOP, 23-gauge TSV may be more beneficial.
比较 23 号经结膜无缝线玻璃体切割术(TSV)和传统 20 号玻璃体切割术治疗各种玻璃体视网膜疾病后的眼压(IOP)。
这是一项回顾性干预性病例系列研究,包括 338 例 23 号 TSV 和 476 例 20 号玻璃体切割术,随访时间至少为 1 个月。比较术后 1 天、1 周和 1 个月的 IOP。采用多元回归分析评估玻璃体切割术的实际效果对术后 IOP 的影响,包括术中及术后影响术后 IOP 的因素作为协变量。
20 号玻璃体切割术的平均 IOP 在术后 1 天明显高于 23 号 TSV(20.6±8.02mmHg 对 12.8±4.48mmHg,P<0.001),但在术后 1 周和 1 个月时差异无统计学意义。23 号 TSV 的 IOP 模式表现出比 20 号玻璃体切割术更稳定的过程。在玻璃体切割术后 1 天,20 号组的高眼压发生率较高,而 23 号组的低眼压发生率较高。在危险因素中,20 号玻璃体切割术与术后 1 天 IOP 升高的相关性最强。
23 号 TSV 在术后早期眼压稳定且较低,对于视网膜和视神经对较高或波动的眼压敏感的患者,23 号 TSV 可能更有益。