School of Dentistry, Aarhus Faculty of Health Sciences, Aarhus University, Aarhus, Denmark.
Caries Res. 2012;46(2):107-12. doi: 10.1159/000336960. Epub 2012 Mar 5.
The aim of this study was to investigate if three probiotic bacteria present in the milk product Cultura Dofilus® naturell could be detected in saliva and on oral mucosal surfaces, and if they colonized dental surfaces in situ in 8 caries-inactive individuals after 8 daily exposures to the milk product for up to 3 days. Bacteria were identified by fluorescence in situ hybridization and confocal laser scanning microscopy. While probiotic bacteria were present sporadically in the oral cavity on mucosal surfaces and in saliva after 3 days of frequent use of the probiotic milk, they were not detected on dental surfaces. Probiotic bacteria may thus contribute to general oral health, but their potential role in biofilm-induced dental diseases remains unclear.
本研究旨在探究在 8 名龋齿非活跃个体中，每日使用含Culturelle Dophilus® naturell 的牛奶产品 8 天，连续 3 天，这些产品中存在的 3 种益生菌是否能在唾液和口腔黏膜表面检测到，以及是否能在牙面原位定植。通过荧光原位杂交和共聚焦激光扫描显微镜对细菌进行鉴定。虽然在频繁使用益生菌牛奶 3 天后，益生菌在口腔黏膜表面和唾液中偶尔存在，但在牙面并未检测到。因此，益生菌可能有助于口腔整体健康，但它们在生物膜诱导的口腔疾病中的潜在作用尚不清楚。
