葡萄糖生物传感器：在临床实践中的应用概述。
Glucose biosensors: an overview of use in clinical practice.
机构信息
Department of Laboratory Medicine, Konyang University Hospital, College of Medical Science, Konyang University, Daejon, Korea.
出版信息
Sensors (Basel). 2010;10(5):4558-76. doi: 10.3390/s100504558. Epub 2010 May 4.
Abstract
Blood glucose monitoring has been established as a valuable tool in the management of diabetes. Since maintaining normal blood glucose levels is recommended, a series of suitable glucose biosensors have been developed. During the last 50 years, glucose biosensor technology including point-of-care devices, continuous glucose monitoring systems and noninvasive glucose monitoring systems has been significantly improved. However, there continues to be several challenges related to the achievement of accurate and reliable glucose monitoring. Further technical improvements in glucose biosensors, standardization of the analytical goals for their performance, and continuously assessing and training lay users are required. This article reviews the brief history, basic principles, analytical performance, and the present status of glucose biosensors in the clinical practice.
摘要
血糖监测已被确立为糖尿病管理的重要工具。由于建议维持正常的血糖水平，因此已经开发出一系列合适的葡萄糖生物传感器。在过去的 50 年中，包括即时检测设备、连续血糖监测系统和无创血糖监测系统在内的葡萄糖生物传感器技术已经得到了显著改善。然而，在实现准确可靠的血糖监测方面仍然存在一些挑战。需要进一步改进葡萄糖生物传感器的技术，标准化其性能的分析目标，并不断评估和培训非专业用户。本文综述了葡萄糖生物传感器在临床实践中的简要历史、基本原理、分析性能和现状。
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