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2 型糖尿病患者从基于初级保健的疾病管理中获益:倾向评分匹配生存时间分析。

Patients with type 2 diabetes benefit from primary care-based disease management: a propensity score matched survival time analysis.

机构信息

Institute of Health Economics and Clinical Epidemiology, University Hospital Cologne, Köln, Germany.

出版信息

Popul Health Manag. 2012 Aug;15(4):241-7. doi: 10.1089/pop.2011.0063. Epub 2012 Mar 8.

DOI:10.1089/pop.2011.0063
PMID:22401149
Abstract

This study aimed to assess the impact of a nationwide German diabetes mellitus disease management program (DMP) on survival time and costs in comparison to routine care. The authors conducted a retrospective observational cohort study using routine administration data from Germany's largest sickness fund to identify insured suffering from diabetes in 2002. A total of 95,443 insured with type 2 diabetes mellitus who were born before January 1, 1962 met the defined inclusion criteria, resulting in 19,888 pairs of DMP participants and nonparticipants matched for socioeconomic and health status using propensity score matching methods. This is the first time propensity score matching has been used to evaluate a survival benefit of DMPs. In the time frame analyzed (3 years), mean survival time for the DMP group was 1045 days vs. 985 days for the routine care group (P<0.001). Mean daily hospital and total costs (including DMP administration and medical costs) were lower for the DMP group in the case of deceased insureds (92€ vs. 139€ and 122€ vs. 169€, respectively) as well as for censored observations (6€ vs. 7€ and 12.9€ vs. 13.4€, respectively). Mean daily drug costs were slightly lower for deceased insured in the DMP group (difference 0.6€), while no identifiable difference was found for censored observations. In this study, insured who were enrolled in a DMP for diabetes mellitus in the German Statutory Health Insurance showed a significant benefit in survival time. They also incurred lower costs compared to propensity score matched insured in routine care.

摘要

本研究旨在评估德国全国性糖尿病疾病管理计划(DMP)对生存时间和成本的影响,并与常规护理进行比较。作者使用德国最大的疾病基金的常规管理数据进行了回顾性观察性队列研究,以确定 2002 年患有糖尿病的参保人。共有 95443 名出生于 1962 年 1 月 1 日前的 2 型糖尿病参保人符合规定的纳入标准,通过倾向评分匹配方法对 DMP 参与者和非参与者进行了 19888 对匹配,以匹配社会经济和健康状况。这是首次使用倾向评分匹配来评估 DMP 的生存获益。在分析的时间范围内(3 年),DMP 组的平均生存时间为 1045 天,而常规护理组为 985 天(P<0.001)。对于已死亡的参保人,DMP 组的每日住院和总费用(包括 DMP 管理和医疗费用)较低(分别为 92 欧元对 139 欧元和 122 欧元对 169 欧元),对于删失观察,DMP 组的每日住院和总费用(分别为 6 欧元对 7 欧元和 12.9 欧元对 13.4 欧元)也较低。对于已死亡的参保人,DMP 组的每日药物费用略低(差异 0.6 欧元),而对于删失观察,未发现明显差异。在这项研究中,参加德国法定健康保险的糖尿病 DMP 的参保人在生存时间上表现出显著的获益。与常规护理中的匹配参保人相比,他们的成本也较低。

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