GeneXpert CT/NG 分析评估，首个用于同时检测淋病奈瑟菌和沙眼衣原体的即时检测基因检测点。
Analytical evaluation of GeneXpert CT/NG, the first genetic point-of-care assay for simultaneous detection of Neisseria gonorrhoeae and Chlamydia trachomatis.
机构信息
Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia.
出版信息
J Clin Microbiol. 2013 Jun;51(6):1945-7. doi: 10.1128/JCM.00806-13. Epub 2013 Apr 3.
Abstract
GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.
摘要
GeneXpert CT/NG 用 372 株具有特征的细菌菌株进行了评估。两种病原体的检测灵敏度均为 10 个基因组拷贝/反应。4 株粘膜炎奈瑟菌和 2 株副流感奈瑟菌分离株的两种淋球菌靶标之一呈阳性；然而，该检测方法将所有结果均标记为阴性。该检测方法具有高度的分析灵敏度和特异性。
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