School of Pharmacy, University of Mississippi, Oxford, MS, USA.
J Nat Med. 2013 Jan;67(1):42-50. doi: 10.1007/s11418-012-0642-2. Epub 2012 Mar 9.
Yohimbine is the major alkaloid found in the stem bark of yohimbe, Pausinystalia johimbe (Rubiaceae), an evergreen tree native to Africa. The objectives of the current study were to provide a detailed anatomy of yohimbe bark, as well as to determine the quantity of yohimbine in the raw yohimbe products sold online. Twelve commercial raw materials of yohimbe were analyzed by microscopic and ultra performance liquid chromatography-UV-MS methods. The study revealed that three samples were probably adulterated and four other samples contained various levels of impurities. Yohimbine was not detected in one sample, whereas its presence in other samples was found to be in the range 0.1-0.91%. The present work also provides a detailed anatomy of the stem bark of yohimbe, with light and scanning electron microscopy images, for proper identification and authentication.
育亨宾是育亨宾树皮（茜草科育亨宾树，原产于非洲的常绿乔木）中的主要生物碱。本研究的目的是提供育亨宾树皮的详细解剖结构，并确定网上销售的原始育亨宾产品中的育亨宾碱含量。通过显微镜和超高效液相色谱-紫外-质谱法分析了 12 种商业用原始育亨宾材料。研究表明，有 3 个样品可能被掺假，还有 4 个样品含有不同程度的杂质。有 1 个样品未检测到育亨宾碱，而其他样品中的含量在 0.1-0.91%之间。本工作还提供了育亨宾树皮的详细解剖结构，包括光镜和扫描电子显微镜图像，以便进行正确的识别和鉴定。
