• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[喉咽反流与喉部相关症状]

[Laryngopharyngeal reflux and larynx-related symptoms].

作者信息

Ptok M, Ptok A

机构信息

Klinik und Poliklinik für Phoniatrie und Pädaudiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

出版信息

HNO. 2012 Mar;60(3):200-5. doi: 10.1007/s00106-011-2441-6.

DOI:10.1007/s00106-011-2441-6
PMID:22402900
Abstract

BACKGROUND

Chronic hoarseness, globus sensation or mucous obstruction are among a wide range of symptoms possibly related to laryngopharyngeal reflux (LPR).

METHOD AND RESULTS

A selective literature research was carried out using PubMed, in which original articles and reviews in German and English were included. Altogether, 2541 articles were found. Despite the large number of publications, there are still open questions regarding aspects of LPR.

DISCUSSION

It can be assumed that refluxate reaching the larynx can damage it. Due to the fact that the symptoms possibly related to LPR can, however, be linked to other causes, a careful consideration of the patient's medical history is of the utmost importance, followed by mandatory laryngoscopy. Diagnostic procedures, such as the trial administration of proton pump inhibitors (PPI) or long-term pH measurement should be used selectively. Depending on the individual symptoms, breathing or voice therapy and/or PPI therapy might be useful. Lifestyle changes including dietary measures should also be contemplated.

摘要

背景

慢性声音嘶哑、咽部异物感或黏液阻塞是一系列可能与喉咽反流(LPR)相关的症状。

方法与结果

使用PubMed进行了选择性文献研究,纳入了德语和英语的原创文章及综述。共找到2541篇文章。尽管有大量出版物,但关于喉咽反流的一些方面仍存在未解决的问题。

讨论

可以认为到达喉部的反流物会对其造成损害。然而,由于可能与喉咽反流相关的症状也可能与其他原因有关,仔细考虑患者的病史至关重要,随后必须进行喉镜检查。诊断程序,如质子泵抑制剂(PPI)的试验性给药或长期pH测量,应选择性使用。根据个体症状,呼吸或嗓音治疗和/或PPI治疗可能会有用。还应考虑包括饮食措施在内的生活方式改变。

相似文献

1
[Laryngopharyngeal reflux and larynx-related symptoms].[喉咽反流与喉部相关症状]
HNO. 2012 Mar;60(3):200-5. doi: 10.1007/s00106-011-2441-6.
2
Evaluation and management of laryngopharyngeal reflux.喉咽反流的评估与管理
JAMA. 2005 Sep 28;294(12):1534-40. doi: 10.1001/jama.294.12.1534.
3
Phonetic Approaches of Laryngopharyngeal Reflux Disease: A Prospective Study.喉咽反流病的语音学方法:一项前瞻性研究。
J Voice. 2017 Jan;31(1):119.e11-119.e20. doi: 10.1016/j.jvoice.2016.02.020. Epub 2016 Apr 25.
4
Evaluation of patients with suspected laryngopharyngeal reflux: a practical approach.疑似喉咽反流患者的评估:一种实用方法。
Curr Gastroenterol Rep. 2011 Jun;13(3):213-8. doi: 10.1007/s11894-011-0184-x.
5
How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related?经喉镜检查怀疑的咽反流病例中有多少与胃食管反流病有关?
World J Gastroenterol. 2012 Aug 28;18(32):4363-70. doi: 10.3748/wjg.v18.i32.4363.
6
Current perspectives on reflux laryngitis.反流性喉炎的当前观点
Clin J Gastroenterol. 2014 Dec;7(6):471-5. doi: 10.1007/s12328-014-0535-x. Epub 2014 Nov 1.
7
Laryngopharyngeal Reflux and Voice Disorders: A Multifactorial Model of Etiology and Pathophysiology.喉咽反流与嗓音障碍:病因学和病理生理学的多因素模型
J Voice. 2017 Nov;31(6):733-752. doi: 10.1016/j.jvoice.2017.03.015. Epub 2017 Apr 21.
8
An update on current treatment strategies for laryngopharyngeal reflux symptoms.咽喉反流症状的当前治疗策略更新。
Ann N Y Acad Sci. 2022 Apr;1510(1):5-17. doi: 10.1111/nyas.14728. Epub 2021 Dec 17.
9
[Pathophysiology, assessment and treatment of laryngopharyngeal reflux].[喉咽反流的病理生理学、评估与治疗]
Rev Laryngol Otol Rhinol (Bord). 2014;135(4-5):163-70.
10
Therapeutic strategies for laryngeal manifestations of gastroesophageal reflux disease.胃食管反流病的喉部表现的治疗策略。
J Clin Gastroenterol. 2013 Mar;47(3):195-204. doi: 10.1097/MCG.0b013e31827458f9.

引用本文的文献

1
[Pharyngeal acid load and different functional endoscopy findings].[咽酸负荷与不同的功能性内镜检查结果]
HNO. 2019 Dec;67(12):940-947. doi: 10.1007/s00106-019-0723-6.
2
Relationship between functional endoscopy and impedance-pH measurement.功能性内镜检查与阻抗-pH测量之间的关系。
HNO. 2017 Aug;65(Suppl 2):116-121. doi: 10.1007/s00106-016-0317-5.
3
[Relationship between functional endoscopy and impedance-pH measurement. German version].[功能性内镜检查与阻抗-pH测量之间的关系。德文版]

本文引用的文献

1
[Extraesophageal reflux. Overview and discussion of a new method for pH monitoring].[食管外反流。pH监测新方法的概述与探讨]
HNO. 2011 Sep;59(9):893-9. doi: 10.1007/s00106-011-2329-5.
2
Review article: reflux and its consequences--the laryngeal, pulmonary and oesophageal manifestations. Conference held in conjunction with the 9th International Symposium on Human Pepsin (ISHP) Kingston-upon-Hull, UK, 21-23 April 2010.综述文章:反流及其后果——喉部、肺部和食管表现。与第 9 届国际人类胃蛋白酶研讨会(ISHP)联合举办的会议,英国赫尔金斯顿,2010 年 4 月 21-23 日。
Aliment Pharmacol Ther. 2011 Apr;33 Suppl 1:1-71. doi: 10.1111/j.1365-2036.2011.04581.x.
3
HNO. 2017 Aug;65(8):657-662. doi: 10.1007/s00106-016-0313-9.
4
[Importance of cellular tight junction complexes in the development of periprosthetic leakage after prosthetic voice rehabilitation].[细胞紧密连接复合体在人工喉康复术后假体周围渗漏发生中的重要性]
HNO. 2015 Mar;63(3):171-2, 174-8, 180-1. doi: 10.1007/s00106-014-2951-0.
5
[Importance of functional endoscopy for diagnostics of extraesophageal reflux : relationship of Belafsky's reflux symptom index and functional endoscopic data].[功能性内镜检查在食管外反流诊断中的重要性:Belafsky反流症状指数与功能性内镜检查数据的关系]
HNO. 2014 Nov;62(11):806-12. doi: 10.1007/s00106-014-2912-7.
A review of clinical practice guidelines for reflux disease: toward creating a clinical protocol for the otolaryngologist.
反流性疾病临床实践指南综述:为耳鼻喉科医生制定临床方案。
Laryngoscope. 2011 Apr;121(4):717-23. doi: 10.1002/lary.21429. Epub 2011 Feb 4.
4
Rationale for targeting pepsin in the treatment of reflux disease.针对胃蛋白酶治疗反流性疾病的理论依据。
Ann Otol Rhinol Laryngol. 2010 Aug;119(8):547-58. doi: 10.1177/000348941011900808.
5
GERD-related chronic laryngitis: pro.胃食管反流病相关的慢性喉炎:专业意见
Arch Otolaryngol Head Neck Surg. 2010 Sep;136(9):910-3. doi: 10.1001/archoto.2010.152.
6
Laryngopharyngeal reflux: current concepts and questions.喉咽反流:当前概念与问题
Curr Opin Otolaryngol Head Neck Surg. 2009 Jun;17(3):143-8. doi: 10.1097/MOO.0b013e32832b2581.
7
Efficacy of esophageal impedance/pH monitoring in patients with refractory gastroesophageal reflux disease, on and off therapy.食管阻抗/pH监测在难治性胃食管反流病患者治疗期间及停药后疗效的研究
Clin Gastroenterol Hepatol. 2009 Jul;7(7):743-8. doi: 10.1016/j.cgh.2009.02.022. Epub 2009 Mar 9.
8
American Gastroenterological Association Institute technical review on the management of gastroesophageal reflux disease.美国胃肠病学会研究所关于胃食管反流病管理的技术综述
Gastroenterology. 2008 Oct;135(4):1392-1413, 1413.e1-5. doi: 10.1053/j.gastro.2008.08.044. Epub 2008 Sep 16.
9
Pathophysiological mechanisms of extraesophageal reflux in otolaryngeal disorders.耳鼻喉疾病中食管外反流的病理生理机制。
Eur Arch Otorhinolaryngol. 2009 Jan;266(1):17-24. doi: 10.1007/s00405-008-0770-1. Epub 2008 Aug 13.
10
The mucosal immune response to laryngopharyngeal reflux.对喉咽反流的黏膜免疫反应。
Am J Respir Crit Care Med. 2008 Jun 1;177(11):1187-93. doi: 10.1164/rccm.200706-895OC. Epub 2008 Mar 6.