Jungheim M, Ptok M
Klinik und Poliklinik für Phoniatrie und Pädaudiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
HNO. 2011 Sep;59(9):893-9. doi: 10.1007/s00106-011-2329-5.
Extraesophageal reflux disease often requires diagnosis and treatment by a phoniatry or ear, nose and throat specialist. The disease needs to be differentiated from gastroesophageal reflux disease.
A new oropharyngeal pH measuring system with a single channel probe has recently been introduced. The aim of this study was to compare oropharyngeal pH-metry with the existing diagnostic methods for extraesophageal reflux disease and to present initial results in our own patients.
A literature search for oropharyngeal pH-metry was performed in the databases NHS EED, HTA, DARE, Clinical trials, Cochrane reviews and Medline/PubMed. A selective literature search was also carried out on the problem of extraesophageal reflux disease.
Evaluation scales, trial proton pump inhibitor therapy or pH-metry, for example, can be used to diagnose extraesophageal reflux disease. pH-metry can be performed using a classical two-channel pH-metry system; a new oropharyngeal pH measuring system has recently been introduced. This new method has been evaluated in initial studies for normative data and has been compared to two-channel pH-metry. Prospective randomised studies to diagnose extraesophageal reflux disease with the new oropharyngeal pH-metry method are still lacking.
Oropharyngeal pH-metry has some potential advantages compared to classical two-channel pH-metry; however, a lot of questions remain unanswered. These will be discussed and illustrated with the help of a number of own patient case reports.
食管外反流病通常需要由言语治疗师或耳鼻喉科专家进行诊断和治疗。该疾病需要与胃食管反流病相鉴别。
最近引入了一种带有单通道探头的新型口咽pH测量系统。本研究的目的是将口咽pH测量法与现有的食管外反流病诊断方法进行比较，并展示我们自己患者的初步结果。
在NHS EED、HTA、DARE、临床试验、Cochrane综述和Medline/PubMed等数据库中对口咽pH测量法进行文献检索。还对食管外反流病问题进行了选择性文献检索。
例如，评估量表、试验性质子泵抑制剂治疗或pH测量法可用于诊断食管外反流病。pH测量法可使用经典的双通道pH测量系统进行；最近引入了一种新型口咽pH测量系统。这种新方法已在初步研究中针对规范数据进行了评估，并与双通道pH测量法进行了比较。目前仍缺乏使用新型口咽pH测量法诊断食管外反流病的前瞻性随机研究。
与经典的双通道pH测量法相比，口咽pH测量法具有一些潜在优势；然而，许多问题仍未得到解答。这些将借助一些自身患者病例报告进行讨论和说明。
