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外科 Apgar 评分在区综合医院中的应用。

Utility of the Surgical Apgar Score in a district general hospital.

机构信息

Department of Surgery, Barnet General Hospital, Wellhouse Lane Barnet, Hertfordshire, EN5 3DJ, UK.

Level 5, St. Marks Hospital, Northwick Park, Watford Road, London, HA1 3UJ, UK.

出版信息

World J Surg. 2012 May;36(5):1066-1073. doi: 10.1007/s00268-012-1495-2.

Abstract

BACKGROUND

The Surgical Apgar Score (SAS) is a simple tool for intraoperative risk stratification. The aim of this prospective observational study was to assess its performance in predicting outcome after general/vascular and orthopedic surgery and its utility in a U.K. district general hospital.

METHOD

A prospective cohort of 223 consecutive general, vascular, and orthopedic surgical cases was studied. The SAS was calculated for all patients, and its relationship to 30 day mortality and major complication assessed with reference to the mode of surgery (elective or emergent). Statistical analysis of categorical data was performed with Fisher's exact test and the AUC (area under the curve) on receiver operating characteristic (ROC) analysis. Selected cases were reviewed to assess the potential of the SAS to modify postoperative management.

RESULTS

The proportion of patients who died or experienced major complications increased monotonically with Surgical Apgar Score category in general and vascular but not orthopedic cases. The relative risks of mortality or major complication between SAS categories were less marked than in previous publications. The SAS performed variably on ROC curve analysis, with an AUC of 0.62-0.73. Discrimination achieved significance in general and vascular cases (p = 0.0002) but not in orthopedic cases (p = 0.15). Subgroup analysis of high (SAS < 7) and low risk (SAS ≥ 7) groups demonstrated utility of the score in general surgery and vascular cases overall (p < 0.0001), and in the emergency (p = 0.004) but not elective (p = 0.12) subgroups. Case note review of those patients who died indicated that despite their identification by the SAS, there would have been limited scope to modify outcome.

CONCLUSION

This study provides further evidence that the SAS is a simple and effective predictive tool in the emergency general and vascular surgical setting. It appears to have a limited role in the management of individual patients after orthopedic surgery and elective general/vascular surgery. The SAS has been proven to reliably stratify risk in larger populations and might be applied most usefully as a marker of quality. Further studies are required to determine whether its application can influence outcome.

摘要

背景

手术 Apgar 评分(SAS)是一种用于术中风险分层的简单工具。本前瞻性观察研究的目的是评估其在预测普通/血管和骨科手术后结果中的表现,并评估其在英国地区综合医院中的应用。

方法

对 223 例连续普通、血管和骨科手术患者进行前瞻性队列研究。对所有患者计算 SAS,并根据手术方式(择期或紧急)评估其与 30 天死亡率和主要并发症的关系。采用 Fisher 精确检验和受试者工作特征(ROC)分析的曲线下面积(AUC)对分类数据进行统计学分析。对选定的病例进行回顾性评估,以评估 SAS 对术后管理的潜在影响。

结果

普通和血管病例中,SAS 类别与死亡或发生重大并发症的患者比例呈单调递增关系,但在骨科病例中则不然。SAS 类别之间的死亡率或主要并发症的相对风险低于先前的文献报道。ROC 曲线分析显示,SAS 的表现各不相同,AUC 为 0.62-0.73。在普通和血管病例中,差异具有统计学意义(p = 0.0002),但在骨科病例中则无统计学意义(p = 0.15)。高(SAS<7)和低风险(SAS≥7)组的亚组分析表明,该评分在普通外科和血管病例中具有实用性(p<0.0001),在急诊(p=0.004)而非择期(p=0.12)亚组中也具有实用性。对死亡患者的病历回顾表明,尽管 SAS 可以识别他们,但对改变结果的影响有限。

结论

本研究进一步证明,SAS 是一种简单有效的预测工具,适用于急诊普通和血管外科环境。它似乎在骨科手术后和择期普通/血管手术后个体患者的管理中作用有限。SAS 已被证明能够可靠地对较大人群进行风险分层,并且可能作为质量标志物最有用。需要进一步的研究来确定其应用是否可以影响结果。

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