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484 例尸肾移植中外科医生经验对并发症发生率和功能结局的影响:单中心回顾性研究。

Impact of surgeon experience on complication rates and functional outcomes of 484 deceased donor renal transplants: a single-centre retrospective study.

机构信息

Department of Urology, Charité University Medicine Berlin, Campus Mitte, Berlin, Germany.

出版信息

BJU Int. 2012 Oct;110(8 Pt B):E368-73. doi: 10.1111/j.1464-410X.2012.011024.x. Epub 2012 Mar 9.

Abstract

OBJECTIVE

To determine how postoperative and functional outcomes after deceased donor renal transplantation (DDRT) are related to surgeon experience.

PATIENTS AND METHODS

The outcomes of 484 adult DDRT performed by 13 urological surgeons were retrospectively reviewed. After completion of a staged renal transplant training programme under supervision of an attending urological transplant surgeon, the 13 surgeons were either assigned to the inexperienced group (n = 8) or the experienced group (n = 5). Surgeons in the experienced group had performed more than 30 unsupervised DDRT in a standard fashion with routine ureteric stenting. Between 1988 and 2005, inexperienced surgeons performed 152 DDRT, whereas experienced surgeons performed 332 DDRT.

RESULTS

Patient and graft survival at 2 hyears were 98% and 94.7%, respectively. Early graft loss in five recipients was unrelated to surgeon experience. Delayed graft function occurred in 29% of cases and median 1-year serum-creatinine was 1.48 mg/dL, with no difference between surgeon groups. Postoperative bleeding and lymphocele formation were the most frequent surgical complications, with an equal distribution between groups. Ureteric complications had a significantly higher incidence among inexperienced surgeons (6.6% versus 2.7%; P = 0.04).

CONCLUSION

We conclude that DDRT as performed by inexperienced urological renal transplant surgeons has both acceptable short- and long-term outcomes.

摘要

目的

确定尸体供肾移植(DDRT)术后和功能结果与外科医生经验的关系。

患者与方法

回顾性分析了 13 名泌尿科医生进行的 484 例成人 DDRT 的结果。在一名主治泌尿科移植外科医生的监督下完成分期肾移植培训计划后,13 名外科医生被分配到经验不足组(n = 8)或经验丰富组(n = 5)。经验丰富组的外科医生以标准方式进行了超过 30 次未经监督的 DDRT,并常规放置输尿管支架。1988 年至 2005 年期间,经验不足的外科医生进行了 152 例 DDRT,而经验丰富的外科医生进行了 332 例 DDRT。

结果

患者和移植物的 2 年存活率分别为 98%和 94.7%。5 名受者的早期移植物丢失与外科医生经验无关。29%的病例发生延迟移植物功能,中位数 1 年血清肌酐为 1.48mg/dL,两组之间无差异。术后出血和淋巴囊肿形成是最常见的手术并发症,两组之间分布均匀。输尿管并发症在经验不足的外科医生中发生率明显更高(6.6%比 2.7%;P = 0.04)。

结论

我们的结论是,经验不足的泌尿科肾移植外科医生进行的 DDRT 具有可接受的短期和长期结果。

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