ESCRT 和钙蛋白酶——旧的和新的关系。
ESCRT and calpain--old and new relationships.
机构信息
Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan.
出版信息
FEBS J. 2012 Apr;279(8):1398. doi: 10.1111/j.1742-4658.2012.08561.x. Epub 2012 Mar 23.
Apparently unrelated systems often merge and work together to achieve diverse biological functions. This minireview series was aimed to unveil new facets of ESCRTs and calpains: ESCRT proteins in MVB formation, virus budding and cell division; the ambient pH sensing and adaptation in association with ESCRTs and the calpain system; evolutionary and physical linkage between calpains and PEF proteins.
显然不相关的系统经常融合并共同工作以实现多样化的生物学功能。本综述系列旨在揭示 ESCRTs 和钙蛋白酶的新方面：ESCRT 蛋白在 MVB 形成、病毒出芽和细胞分裂中的作用；与 ESCRTs 和钙蛋白酶系统相关的环境 pH 感应和适应；钙蛋白酶和 PEF 蛋白之间的进化和物理联系。
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