Department of Surgery Nursing, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Arch Med Sci. 2010 Oct;6(5):793-9. doi: 10.5114/aoms.2010.17097. Epub 2010 Oct 26.
The aim of the research was to compare the dynamics of venous ulcer healing when treated with the use of compression stockings as well as original two- and four-layer bandage systems.
A group of 46 patients suffering from venous ulcers was studied. This group consisted of 36 (78.3%) women and 10 (21.70%) men aged between 41 and 88 years (the average age was 66.6 years and the median was 67). Patients were randomized into three groups, for treatment with the ProGuide two-layer system, Profore four-layer compression, and with the use of compression stockings class II. In the case of multi-layer compression, compression ensuring 40 mmHg blood pressure at ankle level was used.
In all patients, independently of the type of compression therapy, a few significant statistical changes of ulceration area in time were observed (Student's t test for matched pairs, p < 0.05). The largest loss of ulceration area in each of the successive measurements was observed in patients treated with the four-layer system - on average 0.63 cm2/per week. The smallest loss of ulceration area was observed in patients using compression stockings - on average 0.44 cm(2)/per week. However, the observed differences were not statistically significant (Kruskal-Wallis test H = 4.45, p > 0.05).
A systematic compression therapy, applied with preliminary blood pressure of 40 mmHg, is an effective method of conservative treatment of venous ulcers. Compression stockings and prepared systems of multi-layer compression were characterized by similar clinical effectiveness.
本研究旨在比较使用压缩袜和原始的双层和四层绷带系统治疗静脉溃疡愈合的动态。
研究了一组 46 名患有静脉溃疡的患者。该组包括 36 名(78.3%)女性和 10 名(21.70%)男性,年龄在 41 至 88 岁之间(平均年龄为 66.6 岁,中位数为 67 岁)。患者随机分为三组,分别接受 ProGuide 双层系统、Profore 四层压缩治疗和使用 II 级压缩袜治疗。在多层压缩的情况下,使用确保踝部血压为 40mmHg 的压缩。
在所有患者中,无论压缩治疗类型如何,都观察到溃疡面积随时间的几个显著统计学变化(配对学生 t 检验,p<0.05)。在每个连续测量中,溃疡面积损失最大的是接受四层系统治疗的患者-平均每周 0.63cm2。溃疡面积损失最小的是使用压缩袜的患者-平均每周 0.44cm2。然而,观察到的差异没有统计学意义(Kruskal-Wallis 检验 H=4.45,p>0.05)。
系统的压缩治疗,应用 40mmHg 的初步血压,是保守治疗静脉溃疡的有效方法。压缩袜和准备好的多层压缩系统具有相似的临床效果。