Klymiuk O V, Bondzyk O V, Reshetnik Ie M, Vesel's'kyĭ S P, Makarchuk M Iu
Fiziol Zh (1994). 2011;57(6):52-7.
The influence of estron (8 microg/100g of animal's body weight) on the exocrine function of liver and the changes in bile acid composition of bile on different sex rats was studied. It was shown, that hormone at the applied dose, effected choleresis of female rats more effectively. Estron also caused different changes in bile composition. So, estron stimulated bile acid conjugation with taurine and glycin in female rat liver. Increasing of free and conjugated bile acid biosynthesis in male rats was observed.
研究了雌酮（8微克/100克动物体重）对不同性别大鼠肝脏外分泌功能及胆汁酸组成变化的影响。结果表明，在所应用的剂量下，该激素对雌性大鼠胆汁分泌的影响更有效。雌酮还导致胆汁成分发生不同变化。因此，雌酮刺激雌性大鼠肝脏中胆汁酸与牛磺酸和甘氨酸结合。观察到雄性大鼠游离和结合胆汁酸生物合成增加。
