Orenstein M S, Tavitian A, Yonk B, Dincsoy H P, Zerega J, Iyer S K, Straus E W
Gut. 1985 Nov;26(11):1220-5. doi: 10.1136/gut.26.11.1220.
During a one month period liver biopsy was carried out on eight patients with established acquired immune deficiency syndrome (AIDS) and two suspected of having AIDS to evaluate raised liver enzymes or unexplained fever and weight loss. Each of the 10 patients were found to have hepatic granulomas. Appropriate staining techniques showed acid-fast bacilli in seven of the liver specimens. One specimen contained numerous Cryptococcal organisms. Two biopsies showed granulomas but no organisms. Liver biopsy was found to be a high yield and rapid diagnostic procedure in patients with AIDS. Our results suggest that hepatic mycobacterial infection may be more common in the syndrome than previously recognised and that liver biopsy specimens should be examined routinely for the presence of acid-fast bacilli.
在一个月的时间里，对8例确诊为获得性免疫缺陷综合征（艾滋病）的患者和2例疑似患有艾滋病的患者进行了肝活检，以评估肝酶升高或不明原因的发热及体重减轻情况。10例患者均发现有肝肉芽肿。适当的染色技术显示，7份肝脏标本中有抗酸杆菌。1份标本含有大量隐球菌。2份活检显示有肉芽肿但未发现病原体。肝活检被发现是艾滋病患者一种高产出且快速的诊断方法。我们的结果表明，肝分枝杆菌感染在该综合征中可能比以前认识到的更为常见，并且肝活检标本应常规检查是否存在抗酸杆菌。
