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七种用于检测传染性单核细胞增多症中嗜异性抗体的商业检测方法的比较评估。

Comparative evaluation of seven commercial tests for detection of heterophile antibody in infectious mononucleosis.

作者信息

Skulnick M, Low D E, Simor A E, Patel M, George P, Chua R

机构信息

Department of Microbiology, Mount Sinai Hospital, University of Toronto; and Department of Virology, Ministry of Health Laboratory Services Branch, Toronto, Ontario.

出版信息

Can J Infect Dis. 1992 Jan;3(1):23-6. doi: 10.1155/1992/510261.

Abstract

Detection of heterophile antibodies in infectious mononucleosis is the most rapid and cost-effective method for confirming the clinical diagnosis of the disease. This study compared seven commercial test kits (the Oxoid Infectious Mononucleosis Kit [Oxoid Ltd], Immunoscan Im-Latex [Baxter Travenol], Mono-Latex [Wampole Laboratories], Monospot and Im Screen Test [Ortho Diagnostics], Immunoscan Im-RBC Test [Baxter Travenol], and Infectious Mononucleosis Test [NCS Diagnostics]) to the Davidsohn differential test. All of the kits were shown to be acceptable for use, with specificities and sensitivities greater than 96.5% and 95.5%, respectively.

摘要

检测传染性单核细胞增多症中的嗜异性抗体是确诊该病临床诊断的最快速且最具成本效益的方法。本研究将七种商用检测试剂盒(奥克索德传染性单核细胞增多症试剂盒[奥克索德有限公司]、免疫扫描免疫乳胶法[百特医疗用品公司]、单核细胞乳胶法[万波实验室]、嗜异性凝集试验和免疫筛查试验[奥索诊断公司]、免疫扫描免疫红细胞试验[百特医疗用品公司]以及传染性单核细胞增多症检测试剂盒[NCS诊断公司])与戴维森鉴别试验进行了比较。结果表明,所有试剂盒均适用,其特异性和敏感性分别大于96.5%和95.5%。

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False-positive Monospot tests in malaria.疟疾中嗜异性凝集试验的假阳性结果
Am J Clin Pathol. 1974 Feb;61(2):173-5. doi: 10.1093/ajcp/61.2.173.

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