通过偏振敏感光学相干断层扫描自动测量人眼脉络膜厚度。
Automated measurement of choroidal thickness in the human eye by polarization sensitive optical coherence tomography.
作者信息
Torzicky Teresa, Pircher Michael, Zotter Stefan, Bonesi Marco, Götzinger Erich, Hitzenberger Christoph K
机构信息
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, A-1090 Vienna, Austria.
出版信息
Opt Express. 2012 Mar 26;20(7):7564-74. doi: 10.1364/OE.20.007564.
Abstract
We present a new method to automatically segment the thickness of the choroid in the human eye by polarization sensitive optical coherence tomography (PS-OCT). A swept source PS-OCT instrument operating at a center wavelength of 1040 nm is used. The segmentation method is based entirely on intrinsic, tissue specific polarization contrast mechanisms. In a first step, the anterior boundary of the choroid, the retinal pigment epithelium, is segmented based on depolarization. In a second step, the choroid-sclera interface is found by using the birefringence of the sclera. The method is demonstrated in five healthy eyes. The mean repeatability (standard deviation) of thickness measurement was found to be 18.3 µm.
摘要
我们提出了一种通过偏振敏感光学相干断层扫描（PS-OCT）自动分割人眼脉络膜厚度的新方法。使用了一台中心波长为1040 nm的扫频源PS-OCT仪器。该分割方法完全基于内在的、组织特异性的偏振对比机制。第一步，基于去极化分割脉络膜的前边界，即视网膜色素上皮。第二步，利用巩膜的双折射找到脉络膜-巩膜界面。该方法在五只健康眼睛中得到了验证。厚度测量的平均重复性（标准差）为18.3 µm。
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