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桥本甲状腺炎合并四叶甲状腺的罕见病例。

An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland.

作者信息

Dar Rayees Ahmad, Chowdri Nisar Ahmad, Parray Fazl Qadir, Wani Sabiya Hamid

机构信息

Department of General and Minimal Invasive Surgery, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India.

出版信息

N Am J Med Sci. 2012 Mar;4(3):151-3. doi: 10.4103/1947-2714.93881.

DOI:10.4103/1947-2714.93881
PMID:22454831
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3309625/
Abstract

Hashimoto's thyroiditis (HT), an autoimmune disorder, is the most prevalent cause of subclinical or overt hypothyroidism in areas with sufficient iodine intake. The gland is often diffusely enlarged, and the parenchyma is coarsened, hypoechoic, and often hypervascular on ultrasonograpy. Histopathologic appearance of HT includes lymphocyte aggregates with germinal centers, small thyroid follicles, presence of Hurthle cells, and variable fibrosis. We present a case of a 40-year-old female with suspected follicular neoplasm on fine-needle aspiration cytology of neck swelling. Intraoperatively, thyroid gland was found having four lobes separated from each other. Total thyroidectomy was done and histopathology from all four lobes revealed HT. At present, there is no literature to support the fact that such distorted thyroid anatomy may be due to the underlying disease. If we consider it as thyroid gland anomaly, no such anomaly has been mentioned in the literature till date.

摘要

桥本甲状腺炎(HT)是一种自身免疫性疾病,在碘摄入充足的地区,它是亚临床或显性甲状腺功能减退最常见的病因。甲状腺通常呈弥漫性肿大,在超声检查中,实质粗糙、回声减低,且常为高血运。HT的组织病理学表现包括有生发中心的淋巴细胞聚集、小甲状腺滤泡、许特莱细胞的存在以及不同程度的纤维化。我们报告一例40岁女性病例,其颈部肿胀细针穿刺细胞学检查怀疑为滤泡性肿瘤。术中发现甲状腺有四个相互分离的叶。行甲状腺全切除术,所有四个叶的组织病理学检查均显示为HT。目前,尚无文献支持这种甲状腺解剖结构异常可能是由潜在疾病所致这一事实。如果将其视为甲状腺腺体异常,迄今为止文献中尚未提及此类异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989e/3309625/5144abbb820d/NAJMS-4-151-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989e/3309625/51187fed3e98/NAJMS-4-151-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989e/3309625/5144abbb820d/NAJMS-4-151-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989e/3309625/51187fed3e98/NAJMS-4-151-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989e/3309625/5144abbb820d/NAJMS-4-151-g002.jpg

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本文引用的文献

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Thyroid sonography in autoimmune thyroiditis. A prospective study on 123 patients.自身免疫性甲状腺炎的甲状腺超声检查。对123例患者的前瞻性研究。
Acta Endocrinol (Copenh). 1990 Mar;122(3):391-5. doi: 10.1530/acta.0.1220391.