MOH Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, 9# Dong Dan San Tiao, Dongcheng District, Beijing, 100730, People's Republic of China.
Curr Infect Dis Rep. 2012 Jun;14(3):284-91. doi: 10.1007/s11908-012-0258-4.
Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Here we review the epidemiological and clinical characteristics of recently identified viruses including human metapneumovirus, human coronaviruses NL63 and HKU1, human rhinovirus C, bocavirus, WU and KI polyomaviruses, and parechovirus. The roles of these viruses in LRTIs in children and adults are discussed.
下呼吸道感染(LRTIs)是全球公共卫生的负担,常由呼吸道病毒引起。分子诊断技术的进步使以前未被发现的病毒病原体得以识别,并增进了我们对呼吸道病毒感染的认识。在此,我们综述了最近发现的病毒,包括人偏肺病毒、人冠状病毒 NL63 和 HKU1、人鼻病毒 C、博卡病毒、WU 和 KI 多瘤病毒以及副流感病毒的流行病学和临床特征。讨论了这些病毒在儿童和成人 LRTIs 中的作用。