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桦褐孔菌提取物对细胞培养中丙型肝炎病毒感染的抗病毒活性。

Antiviral activity of Inonotus obliquus fungus extract towards infection caused by hepatitis C virus in cell cultures.

作者信息

Shibnev V A, Mishin D V, Garaev T M, Finogenova N P, Botikov A G, Deryabin P G

机构信息

D. I. Ivanovsky Institute of Virology, Ministry of Health Care and Social Development of the Russian Federation, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2011 Sep;151(5):612-4. doi: 10.1007/s10517-011-1395-8.

DOI:10.1007/s10517-011-1395-8
PMID:22462058
Abstract

Fractions of Inonotus obliquus fungus water extract exhibited a virucidal effect towards hepatitis C virus: it 100-fold reduced its infective properties within 10 min. The antiviral effects of fungus extracts manifested after preventive (24 h before infection) and therapeutic use (during infection of porcine embryo kidney cells). Moreover, the data indicate that the birch fungus extracts inhibit production of infective virus by porcine embryo kidney cells.

摘要

桦褐孔菌水提取物的各组分对丙型肝炎病毒具有杀病毒作用

在10分钟内可使其感染性降低100倍。真菌提取物的抗病毒作用在预防性使用(感染前24小时)和治疗性使用(猪胚胎肾细胞感染期间)后均有体现。此外,数据表明桦褐孔菌提取物可抑制猪胚胎肾细胞产生有感染性的病毒。

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