Institute of Health and Welfare Policy, National Yang-Ming University, Taipei, Taiwan.
Urology. 2012 Jun;79(6):1355-9. doi: 10.1016/j.urology.2012.01.036. Epub 2012 Apr 1.
To investigate the prevalence, incidence, associated risk factors, and treatment of pediatric urolithiasis in Taiwan.
The present study used a subset of the National Health Insurance Research Database, known as the Longitudinal Health Insurance Database 2005, which contains the data for all paid medical benefit claims from 1997 to 2006 for a subset of 1 million beneficiaries randomly drawn from the population of 22.72 million individuals during any part of the calendar year 2005. Our analysis included the data of all newly diagnosed pediatric patients with an "International Classification of Disease, 9th revision," diagnosis of urolithiasis from 1997 through 2006.
A total of 1679 pediatric subjects who had newly diagnosed urolithiasis without a previous attack were identified from 1997 to 2006 as the study sample. Of the 1679 patients, 808 were boys (48.1%) and 871 were girls (51.9%). The incidence rate of urolithiasis in 2005 was 0.047%. The peak age of pediatric stone occurrence in the study sample was 15-18 years (49.6%). The most common associated disease was urinary tract infection (34.1% of all subjects). The occurrence rate of pediatric urolithiasis correlated significantly with the urbanization level of the residence and geographic area.
Using a nationwide, population-based study provides important clinical and epidemiologic information regarding pediatric urolithiasis. Additional studies are warranted to determine the effect of geographic area and urbanization level on the occurrence of pediatric stone disease.
调查台湾地区儿童尿石症的患病率、发病率、相关危险因素和治疗方法。
本研究使用了国家健康保险研究数据库（NHIRD）的一个子集，即 2005 年纵向健康保险数据库，该数据库包含了 1997 年至 2006 年期间从 2272 万人口中随机抽取的 100 万参保者的所有付费医疗受益索赔数据。我们的分析包括了 1997 年至 2006 年期间所有新诊断为尿石症的儿科患者的资料，这些患者的诊断均符合国际疾病分类第 9 版（ICD-9）。
本研究共纳入了 1997 年至 2006 年间新诊断为无既往发作的尿石症的 1679 例儿科患者，作为研究样本。在 1679 例患者中，男孩 808 例（48.1%），女孩 871 例（51.9%）。2005 年尿石症的发病率为 0.047%。研究样本中儿童结石发病的高峰年龄为 15-18 岁（49.6%）。最常见的相关疾病是尿路感染（占所有患者的 34.1%）。儿科尿石症的发生率与居住地的城市化水平和地理区域显著相关。
采用基于人群的全国性研究，为儿童尿石症提供了重要的临床和流行病学信息。需要进一步研究确定地理区域和城市化水平对儿童结石病发生的影响。
