Research Centre on Aging Health and Social Services Centre, Institute of Geriatrics, Sherbrooke University, Sherbrooke, Québec, Canada.
Menopause. 2012 Sep;19(9):1015-21. doi: 10.1097/gme.0b013e318248f50f.
The aim of this study was to investigate the impact of caloric restriction (CR) and resistance training (RT) on body composition, metabolic profile and physical capacity in dynapenic-obese postmenopausal women.
Thirty-eight dynapenic-obese postmenopausal (age, 62.6 ± 4.1 y) women were randomly assigned to one of four groups (1, CR; 2, RT; 3, CR + RT; and 4, control) for a 12-week intervention. The independent variables were body weight, fat mass, and lean body mass (using dual-energy x-ray absorptiometry), waist circumference, fasting lipids and glucose, resting systolic and diastolic blood pressure, and physical capacity (6-min walk, chair stand, and one-leg stand tests).
Body weight, fat mass, and waist circumference decreased similarly in the CR and CR + RT groups (all P ≤ 0.05). However, only changes in the CR + RT group were significantly different from the control group (all P ≤ 0.05). Total cholesterol, triglycerides, and systolic and diastolic blood pressure significantly decreased in the CR group (all P ≤ 0.05); whereas total cholesterol, low-density lipoprotein cholesterol, and systolic blood pressure decreased in the CR + RT group (P ≤ 0.05). Physical capacity improved significantly in the RT and CR + RT groups (all P ≤ 0.05), with significant greater improvements in the RT group (P ≤ 0.05).
Our results suggest that CR with or without RT is effective in improving metabolic profile, whereas RT is effective in improving physical capacity. The combination of RT and CR may be particularly relevant in maximizing improvements in physical capacity in dynapenic-obese postmenopausal women.
本研究旨在探讨热量限制（CR）和抗阻训练（RT）对动力不足型肥胖绝经后妇女身体成分、代谢特征和身体能力的影响。
38 名动力不足型肥胖绝经后妇女（年龄 62.6±4.1 岁）被随机分为 4 组（1、CR；2、RT；3、CR+RT；4、对照组），进行 12 周干预。独立变量为体重、脂肪量和瘦体量（使用双能 X 射线吸收法）、腰围、空腹血脂和血糖、静息收缩压和舒张压以及身体能力（6 分钟步行、坐站和单腿站立测试）。
CR 和 CR+RT 组的体重、脂肪量和腰围均明显下降（均 P≤0.05）。然而，只有 CR+RT 组的变化与对照组有显著差异（均 P≤0.05）。CR 组总胆固醇、甘油三酯、收缩压和舒张压显著下降（均 P≤0.05）；而 CR+RT 组总胆固醇、低密度脂蛋白胆固醇和收缩压下降（P≤0.05）。RT 和 CR+RT 组的身体能力显著提高（均 P≤0.05），其中 RT 组的提高更为显著（P≤0.05）。
我们的结果表明，CR 联合或不联合 RT 均能有效改善代谢特征，而 RT 则能有效改善身体能力。RT 联合 CR 可能特别有助于最大限度地提高动力不足型肥胖绝经后妇女的身体能力。
