Center for Reducing Health Disparities, MetroHealth Campus of Case Western Reserve University, Case Western Reserve University, Cleveland Minority Organ Tissue Transplant Education Program, Ohio, USA.
Ann Intern Med. 2012 Apr 3;156(7):483-90. doi: 10.7326/0003-4819-156-7-201204030-00004.
The gap between the supply of organs available for transplantation and demand is growing, especially among ethnic groups.
To evaluate the effect of a video designed to address concerns of ethnic groups about organ donation.
Cluster randomized, controlled trial. Randomization was performed by using a random-number table with centralized allocation concealment. Participants and investigators assessing outcomes were not blinded to group assignment. (ClinicalTrials.gov registration number: NCT00870506)
Twelve branches of the Ohio Bureau of Motor Vehicles in northeastern Ohio.
952 participants aged 15 to 66 years.
Video (intervention; n = 443) or usual Bureau of Motor Vehicles license practices (control; n = 509).
The primary outcome was the proportion of participants who provided consent for organ donation on a newly acquired driver's license, learner's permit, or state identification card. Secondary outcomes included willingness to make a living kidney donation to a family member in need and personal beliefs about donation.
More participants who viewed the video consented to donate organs than control participants (84% vs. 72%; difference, 12 percentage points [95% CI, 6 to 17 percentage points]). The video was effective among black participants (76% vs. 54%; difference, 22 percentage points [CI, 9 to 35 percentage points]) and white participants (88% vs. 77%; difference, 11 percentage points [CI, 5 to 15 percentage points]). At the end of the trial, fewer intervention than control participants reported having insufficient information about organ donation (34% vs. 44%; difference, -10 percentage points [CI, -16 to -4 percentage points]), wanting to be buried with all of their organs (14% vs. 25%; difference, -11 percentage points [CI, -16 to -6 percentage points]), and having conflicts with organ donation (7% vs. 11%; difference, -4 percentage points [CI, -8 to -2 percentage points]).
How the observed increases in consent to donate organs might translate into a greater organ supply in the region is unclear.
Exposure to a brief video addressing concerns that ethnic groups have about organ donation just before obtaining a license, permit, or identification card increased consent to donate organs among white and black participants.
National Institutes of Health and the Robert Wood Johnson Foundation.
器官移植的供应与需求之间的差距越来越大，尤其是在少数民族群体中。
评估一段旨在解决少数民族群体对器官捐献的担忧的视频的效果。
整群随机对照试验。使用随机数字表和集中式隐藏进行随机分组。参与者和评估结果的调查人员对分组分配不知情。（临床试验.gov 注册号：NCT00870506）
俄亥俄州东北部的俄亥俄州机动车局的 12 个分支机构。
952 名年龄在 15 至 66 岁之间的参与者。
视频（干预组；n = 443）或机动车局的常规驾照发放实践（对照组；n = 509）。
主要结果是在新获得的驾驶执照、学习许可证或州身份证上，同意器官捐献的参与者比例。次要结果包括愿意向有需要的家庭成员捐赠活体肾脏以及个人对捐赠的看法。
观看视频的参与者比对照组更愿意捐献器官（84%对 72%；差异，12 个百分点[95%置信区间，6 至 17 个百分点]）。该视频对黑人参与者（76%对 54%；差异，22 个百分点[95%置信区间，9 至 35 个百分点]）和白人参与者（88%对 77%；差异，11 个百分点[95%置信区间，5 至 15 个百分点]）均有效。在试验结束时，与对照组相比，干预组报告对器官捐献的信息了解不足的参与者更少（34%对 44%；差异，-10 个百分点[95%置信区间，-16 至-4 个百分点]），希望死后完整保留自己器官的参与者更少（14%对 25%；差异，-11 个百分点[95%置信区间，-16 至-6 个百分点]），以及存在器官捐献冲突的参与者更少（7%对 11%；差异，-4 个百分点[95%置信区间，-8 至-2 个百分点]）。
该地区通过观察增加的同意捐赠器官的数量如何转化为更大的器官供应尚不清楚。
在获得驾照、许可证或身份证之前，观看一段简短的视频来解决少数民族群体对器官捐献的担忧，可以增加白人和黑人参与者捐献器官的意愿。
美国国立卫生研究院和罗伯特·伍德·约翰逊基金会。
