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墨西哥功能性胃肠病的流行病学:一项基于人群的研究。

The epidemiology of functional gastrointestinal disorders in Mexico: a population-based study.

机构信息

Puebla Research Coordination, Instituto Mexicano del Seguro Social, CP 72000 Puebla-PUE, Mexico.

出版信息

Gastroenterol Res Pract. 2012;2012:606174. doi: 10.1155/2012/606174. Epub 2012 Mar 19.

DOI:10.1155/2012/606174
PMID:22474443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3313569/
Abstract

Aims. The frequency of functional gastrointestinal disorders (FGIDs) in the general population of Mexico is unknown. Methods. To determine the prevalence of FGIDs, associated depression, and health care utilization, a population-based sampling strategy was used to select 500 households in the State of Tlaxcala, in central Mexico. Household interviews were conducted by two trained physicians using the Rome II Modular Questionnaire, a health-care and medication used questionnaire and the CES-D depression scale. Results. The most common FGIDs were IBS: 16.0% (95% CI: 12.9-19.5); functional bloating: 10.8% (8.2-13.9); unspecified functional bowel disorder: 10.6% (8.0-13.6); and functional constipation (FC): 7.4% (5.3-10.1). Uninvestigated heartburn was common: 19.6% (16.2-23.4). All FGIDs were equally prevalent among both genders, except for IBS (P = 0.001), IBS-C (P < 0.001), IBS-A/M (P = 0.049), and FC (P = 0.039) which were more frequent in women. Subjects with FGIDs reported higher frequencies of medical visits: 34.6 versus 16.8%; use of medications: 40.7 versus 21.6%; (both P < 0.001); and reported depression: 26.7 versus 6.7%, (P < 0.001). Conclusion. In this first population-based study of FGIDs in Mexico, heartburn, IBS, functional distension, and FC were common. Only IBS, IBS-C, IBS-A/M, and FC were more frequent in women. Finally, FGIDs in Mexico had an increased burden of health care utilization and depression.

摘要

目的。墨西哥普通人群中功能性胃肠疾病(FGIDs)的频率尚不清楚。方法。为了确定 FGIDs、相关抑郁和医疗保健利用的患病率,采用基于人群的抽样策略在墨西哥中部的塔瓦斯科州选择了 500 户家庭。两名经过培训的医生使用罗马 II 模块问卷、医疗保健和药物使用问卷以及 CES-D 抑郁量表对家庭进行访谈。结果。最常见的 FGIDs 是 IBS:16.0%(95%CI:12.9-19.5);功能性腹胀:10.8%(8.2-13.9);未指定的功能性肠病:10.6%(8.0-13.6);和功能性便秘(FC):7.4%(5.3-10.1)。未经调查的烧心很常见:19.6%(16.2-23.4)。所有 FGIDs 在两性中的患病率均相等,除了 IBS(P=0.001)、IBS-C(P<0.001)、IBS-A/M(P=0.049)和 FC(P=0.039),这些在女性中更为常见。FGIDs 患者报告的就诊次数更高:34.6 次与 16.8 次;使用药物的频率更高:40.7 次与 21.6 次;(均 P<0.001);报告抑郁的频率更高:26.7%与 6.7%;(P<0.001)。结论。在墨西哥进行的首次 FGIDs 基于人群的研究中,烧心、IBS、功能性腹胀和 FC 很常见。只有 IBS、IBS-C、IBS-A/M 和 FC 在女性中更为常见。最后,墨西哥的 FGIDs 增加了医疗保健利用和抑郁的负担。

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