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A novel anticancer diterpenoid from Jatropha gossypifolia.

作者信息

Falodun Abiodun, Kragl Udo, Touem Serge-Mitherand Tengho, Villinger Alexander, Fahrenwaldt Thomas, Langer Peter

机构信息

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, Benin City, Nigeria, Edo State 30001.

出版信息

Nat Prod Commun. 2012 Feb;7(2):151-2.

Abstract

Jatropha gossypifolia root bark is used in ethnomedicine for bacterial infections and cancer of the lungs. Phytochemical investigation resulted in the isolation and characterization of a potent anticancer and novel lathyrane diterpenoid compound, abiodone, with an unusual methylene group. The structure of this novel compound was established by 1D, and 2D NMR spectroscopic experiments a nd confirmed by X-ray analysis.

摘要

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