Suppr超能文献

购买者需谨慎:阿育吠陀医学导致的铅中毒。

Buyers beware: lead poisoning due to Ayurvedic medicine.

机构信息

University of Alabama at Birmingham, Birmingham, AL, USA.

出版信息

J Gen Intern Med. 2012 Oct;27(10):1384-6. doi: 10.1007/s11606-012-2048-y. Epub 2012 Apr 3.

Abstract

A 29-year-old man, who recently emigrated from India, presented with a 2-week history of abdominal pain, as well as nausea, constipation, and fatigue. He underwent removal of a parathyroid adenoma 6 weeks prior to admission and received a locally made Indian traditional medicine (Ayurveda) for pain control; however, this information was not initially available. He was instructed to take approximately 15 g/day. Initial evaluation revealed a normocytic anemia, but other workup including imaging and endoscopy was unrevealing. Given his recent use of Ayurvedic medicines, we tested for lead poisoning and found a blood lead level of 72 mcg/dl. We sent his medicine for analysis and found it had a high lead concentration of 36,000 mcg/g, which is over 25,000 times the maximum daily dose. He improved with cessation of the medicine and treatment with succimer. Lead poisoning can present with a variety of nonspecific signs and symptoms, including abdominal pain and anemia. Ayurvedic medicines, as well as traditional medicines from other cultures, may be a source of lead or other heavy metals. It is essential for physicians to be aware of adverse effects of Ayurvedic medicines as they are easily available and increasing in popularity.

摘要

一位 29 岁的男性,最近从印度移民而来,出现了腹痛、恶心、便秘和疲劳的症状,持续了两周。他在入院前 6 周接受了甲状旁腺瘤切除术,并接受了一种当地生产的印度传统药物(阿育吠陀)进行止痛治疗;然而,这些信息最初并未提供。他被指示每天服用约 15 克。初步评估显示为正细胞正色素性贫血,但其他检查,包括影像学和内镜检查,均未发现异常。鉴于他最近使用了阿育吠陀药物,我们检测了铅中毒情况,发现他的血铅水平为 72 mcg/dl。我们将他的药物送去进行分析,发现其中含有高浓度的铅,浓度为 36000 mcg/g,超过了每日最大剂量的 25000 倍。他停止服用药物并接受了二巯丁二酸治疗后有所改善。铅中毒可能会出现多种非特异性症状,包括腹痛和贫血。阿育吠陀药物以及来自其他文化的传统药物可能是铅或其他重金属的来源。医生必须意识到阿育吠陀药物的不良反应,因为这些药物很容易获得且越来越受欢迎。

相似文献

1
Buyers beware: lead poisoning due to Ayurvedic medicine.
J Gen Intern Med. 2012 Oct;27(10):1384-6. doi: 10.1007/s11606-012-2048-y. Epub 2012 Apr 3.
2
Ayurvedic plumbism.
Intern Med J. 2017 Jul;47(7):823-825. doi: 10.1111/imj.13478.
3
Ayurvedic herbal medicine and lead poisoning.
J Hematol Oncol. 2011 Dec 20;4:51. doi: 10.1186/1756-8722-4-51.
5
Lead intoxication due to ayurvedic medications as a cause of abdominal pain in adults.
Clin Toxicol (Phila). 2017 Feb;55(2):97-101. doi: 10.1080/15563650.2016.1259474. Epub 2016 Dec 13.
6
Lead poisoning from Ayurvedic medicines.
N Z Med J. 2013 May 10;126(1374):80-3.
7
[Severe lead poisoning caused by ayurvedic medicine].
Dtsch Med Wochenschr. 2022 Mar;147(5):253-257. doi: 10.1055/a-1743-6718. Epub 2022 Feb 28.
8
[Lead poisoning after ingestion of ayurvedic drugs].
Med Klin (Munich). 2004 Aug 15;99(8):476-80. doi: 10.1007/s00063-004-1072-2.
9
Lead poisoning from Ayurvedic treatment: a further case.
Med Lav. 2021 Apr 20;112(2):162-167. doi: 10.23749/mdl.v112i2.10576.
10
A young Indian male with abdominal pain.
Clin Toxicol (Phila). 2011 Mar;49(3):191-2. doi: 10.3109/15563650.2011.559474.

引用本文的文献

1
Lead and arsenic intoxications by traditional and alternative medicine: men are more sensitive than women.
Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan;398(1):799-818. doi: 10.1007/s00210-024-03317-y. Epub 2024 Jul 27.
3
Are Ayurvedic medications store house of heavy metals?
Toxicol Res (Camb). 2022 Jan 15;11(1):179-183. doi: 10.1093/toxres/tfab124. eCollection 2022 Feb.
4
Toxic metals in ayurvedic preparations from a public health lead poisoning cluster investigation.
Int J Occup Environ Health. 2017 Jul;23(3):187-192. doi: 10.1080/10773525.2018.1447880. Epub 2018 Mar 12.
5
Case of acute lead toxicity associated with Ayurvedic supplements.
BMJ Case Rep. 2016 Jun 30;2016:bcr2016215041. doi: 10.1136/bcr-2016-215041.

本文引用的文献

1
Adult blood lead epidemiology and surveillance--United States, 2008-2009.
MMWR Morb Mortal Wkly Rep. 2011 Jul 1;60(25):841-5.
3
Dimercaptosuccinic acid (succimer; DMSA) in inorganic lead poisoning.
Clin Toxicol (Phila). 2009 Aug;47(7):617-31. doi: 10.1080/15563650903174828.
7
Recommendations for medical management of adult lead exposure.
Environ Health Perspect. 2007 Mar;115(3):463-71. doi: 10.1289/ehp.9784. Epub 2006 Dec 22.
8
Heavy metal content of ayurvedic herbal medicine products.
JAMA. 2004 Dec 15;292(23):2868-73. doi: 10.1001/jama.292.23.2868.
9
The use and safety of non-allopathic Indian medicines.
Drug Saf. 2002;25(14):1005-19. doi: 10.2165/00002018-200225140-00003.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验