Lewis H M, Parry J V, Davies H A, Parry R P, Mott A, Dourmashkin R R, Sanderson P J, Tyrrell D A, Valman H B
Arch Dis Child. 1979 May;54(5):339-46. doi: 10.1136/adc.54.5.339.
In a hospital study rotavirus was identified in 51% of 152 children with diarrhoea. These patients showed a clinical pattern that was distinct from patients in whom the diarrhoea was associated with bacteria, other viruses, or no pathogens. A respiratory illness was described in 66% of rotavirus patients and usually preceded the gastrointestinal symptoms. Vomiting lasted between one and 3 days and was curtailed by substituting the normal diet with clear fluids. Watery diarrhoes continued for 4 or 5 days, even when rehydration was by the intravenous rather than the oral route. Prolonged diarrhoea was rare. Most children infected with rotavirus were under 2 years of age, but dehydration was most severe in infants aged between 12 and 18 months. A clinician can thus recognise the rotavirus syndrome and expect spontaneous recovery if adequate rehydration is maintained for a critical few days.
在一项医院研究中,152名腹泻儿童中有51%检测出轮状病毒。这些患者呈现出一种与腹泻由细菌、其他病毒或无病原体引起的患者不同的临床症状。66%的轮状病毒患者出现过呼吸道疾病,且通常先于胃肠道症状出现。呕吐持续1至3天,通过用清澈液体替代正常饮食可缓解。即便通过静脉而非口服途径补液,水样腹泻仍会持续4或5天。持续性腹泻较为罕见。大多数感染轮状病毒的儿童年龄在2岁以下,但12至18个月大的婴儿脱水最为严重。因此,临床医生可以识别轮状病毒综合征,并预期如果在关键的几天内保持充分补液,患者会自然康复。